NCT07365566Recruiting
Pain Assessment in Patients With Idiopathic Rapid Eye Movement (REM) Sleep Behaviour Disorder
Pain Assessment in Patients With Idiopathic REM Sleep Behaviour Disorder
Source: ClinicalTrials.gov · Last updated 1 May 2026
Brief summary (registry, in English)
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, with over 12 million patients expected globally by 2040. The disease is currently diagnosed at the appearance of motor symptoms, but by then, over 60% of striatal dopaminergic neurons have already been destroyed. Prodromal symptoms such as idiopathic REM Sleep Behavior Disorder (iRBD), anosmia, mood disorders and constipation appear earlier and are listed as criteria for a prodromal PD diagnosis. Identifying early signs is critical to initiate neuroprotective treatments as early as possible. While pain is prevalent and highly disabling in early PD, no data are currently available on pain perception in iRBD patients, whose condition is of the main risk factor for PD development.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- First submitted
- 16 Jan 2026
- Start date
- 24 Feb 2026
- Primary completion date
- Aug 2026
- Lead sponsor
- University Hospital, Toulouse
- Diseases
- Parkinson disease
- NCT number
- NCT07365566
What you commit to
- Study type: Interventional
- Planned participants: 24
- From 24 Feb 2026 to the primary completion date, Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Diagnosed Parkinson's Disease, dementia with Lewy bodies or multiple system atrophy;
- Severe depression according to Diagnostic and Statistical Manual of Mental Disorders (DSM V);
Other
- Inability to complete study procedures or questionnaires.
Who the study is looking for
- Diagnosed with iRBD confirmed by polysomnography;
- No clinical diagnosis of Parkinson's disease or other diagnosis of neurodegenerative disease;
- Ability to understand and complete study procedures and questionnaires;
- Control group:
- Diagnosed with narcolepsy type 1;
- Coexisting REM sleep behavior disorder confirmed by polysomnography;
- Ability to understand and complete study procedures and questionnaires;
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Expert Parkinson Hôpital Pierre Paul Riquet Place du Docteur Baylac Coordinator of this site? Confirm its status | Toulouse | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.