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NCT07366684Recruiting

Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome

Investigation of Clinical Characteristics, Frailty, and Predictors of In-Hospital and Six-Month Prognosis in Hospitalized Patients Aged 75 Years and Older With Acute Coronary Syndrome

Source: ClinicalTrials.gov · Last updated 15 May 2026

Brief summary (registry, in English)

This study will evaluate clinical characteristics, frailty, and predictors of prognosis in patients aged 75 years and older who are hospitalized with acute coronary syndrome (ACS). The research includes both a retrospective and a prospective cohort. The aim is to determine whether frailty scores, combined with clinical and laboratory parameters available at admission, can improve risk prediction for complications and mortality compared with standard risk scores (TIMI, GRACE, Syntax). The study will also compare outcomes between patients treated with percutaneous coronary intervention (PCI) and those treated conservatively with medications. Patients will be followed during hospitalization and for six months after discharge. The results are expected to contribute to more personalized treatment strategies for elderly patients with ACS.

Status (registry)
Recruiting
Study type
Observational
Enrollment
550 (estimated)
First submitted
1 Dec 2025
Start date
13 May 2026
Primary completion date
Mar 2027
Lead sponsor
Clinical Center Niš
NCT number
NCT07366684

What you commit to

  • Study type: Observational
  • Planned participants: 550
  • From 13 May 2026 to the primary completion date, Mar 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Refusal to provide informed consent (prospective cohort)
  • Missing or incomplete medical documentation (retrospective cohort)

Who the study is looking for

  • Age ≥ 75 years
  • Diagnosis of acute coronary syndrome (STEMI, NSTEMI, or unstable angina)
  • Hospitalization in a tertiary care center (University Clinical Center Niš)
  • For prospective cohort: signed informed consent

Age in the registry: 75 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Clinical Center Nis
Coordinator of this site? Confirm its status
NišSerbiaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.