NCT07366684Recruiting
Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome
Investigation of Clinical Characteristics, Frailty, and Predictors of In-Hospital and Six-Month Prognosis in Hospitalized Patients Aged 75 Years and Older With Acute Coronary Syndrome
Source: ClinicalTrials.gov · Last updated 15 May 2026
Brief summary (registry, in English)
This study will evaluate clinical characteristics, frailty, and predictors of prognosis in patients aged 75 years and older who are hospitalized with acute coronary syndrome (ACS). The research includes both a retrospective and a prospective cohort. The aim is to determine whether frailty scores, combined with clinical and laboratory parameters available at admission, can improve risk prediction for complications and mortality compared with standard risk scores (TIMI, GRACE, Syntax). The study will also compare outcomes between patients treated with percutaneous coronary intervention (PCI) and those treated conservatively with medications. Patients will be followed during hospitalization and for six months after discharge. The results are expected to contribute to more personalized treatment strategies for elderly patients with ACS.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 550 (estimated)
- First submitted
- 1 Dec 2025
- Start date
- 13 May 2026
- Primary completion date
- Mar 2027
- Lead sponsor
- Clinical Center Niš
- Diseases
- Coronary artery disease
- NCT number
- NCT07366684
What you commit to
- Study type: Observational
- Planned participants: 550
- From 13 May 2026 to the primary completion date, Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Refusal to provide informed consent (prospective cohort)
- Missing or incomplete medical documentation (retrospective cohort)
Who the study is looking for
- Age ≥ 75 years
- Diagnosis of acute coronary syndrome (STEMI, NSTEMI, or unstable angina)
- Hospitalization in a tertiary care center (University Clinical Center Niš)
- For prospective cohort: signed informed consent
Age in the registry: 75 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinical Center Nis Coordinator of this site? Confirm its status | Niš | Serbia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.