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NCT07367893Recruiting

Exercise Echocardiography Registry for Ischemic and Non-Ischemic Heart Disease

Source: ClinicalTrials.gov · Last updated 22 May 2026

Brief summary (registry, in English)

Exercise echocardiography is a widely used non-invasive test that evaluates cardiac structure and function during physical stress. It provides important information on myocardial ischemia, cardiac performance, hemodynamic responses, and exercise capacity in patients with a broad range of heart diseases. However, real-world prospective data integrating exercise echocardiographic findings across both ischemic and non-ischemic heart disease remain limited. This prospective observational registry aims to systematically collect clinical, exercise, and echocardiographic data from patients undergoing clinically indicated exercise echocardiography. The registry includes patients with suspected or established ischemic heart disease as well as those with non-ischemic cardiac conditions, such as cardiomyopathies, heart failure, valvular heart disease, and exercise-related symptoms. The collected data will be used to evaluate exercise-induced changes in cardiac structure and function, identify phenotypes associated with adverse clinical outcomes, and improve risk stratification in routine clinical practice. The registry is observational in nature and does not alter standard clinical care.

Status (registry)
Recruiting
Study type
Observational
Enrollment
10000 (estimated)
First submitted
30 Dec 2025
Start date
1 Apr 2026
Primary completion date
31 Dec 2030
Lead sponsor
Yonsei University
NCT number
NCT07367893

What you commit to

  • Study type: Observational
  • Planned participants: 10000
  • From 1 Apr 2026 to the primary completion date, 31 Dec 2030
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Inability to perform exercise testing due to non-cardiac limitations, such as severe orthopedic, neurologic, or pulmonary conditions
  • Any condition deemed by the treating physician to make participation inappropriate or unsafe, even within an observational framework

Other

  • Poor echocardiographic image quality that does not allow meaningful interpretation of exercise-induced changes

Who the study is looking for

  • Adults aged 18 years or older
  • Patients referred for clinically indicated exercise echocardiography as part of routine clinical care
  • Patients evaluated for suspected or known ischemic heart disease, or non-ischemic heart disease, including but not limited to: Cardiomyopathy, Heart failure, Valvular heart disease, Structural heart disease
  • Ability to perform exercise-based stress testing using treadmill or bicycle protocols
  • Availability of baseline clinical data and interpretable echocardiographic images obtained during rest and exercise
  • Provision of informed consent, or eligibility for consent waiver in accordance with institutional review board approval

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Yonsei University Yongin Severance Hospital
Coordinator of this site? Confirm its status
YonginSouth KoreaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.