NCT07368400Not yet recruiting
DMD and Gamified Physiotherapy
Development and Investigation of the Effectiveness of a Gamified Mobile Physical Therapy Exercise Application for Children With Duchenne Muscular Dystrophy: A 6-Month Follow-Up Single-Blind Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 27 Jan 2026
Brief summary (registry, in English)
Duchenne Muscular Dystrophy (DMD) is a progressive neuromuscular disease that limits children's physical function, mobility, and participation in daily life. Regular physiotherapy and exercise are essential to slow functional decline; however, many children experience difficulties maintaining motivation and adherence to long-term exercise programs. Low adherence leads to reduced treatment benefit and faster loss of motor abilities. This study aims to investigate whether a gamified mobile physiotherapy exercise program can improve participation, motivation, and physical outcomes in children with DMD. The mobile program includes personalized exercises designed by physiotherapists and occupational therapists, combined with game-based elements such as rewards, levels, feedback, and virtual achievements to enhance engagement. The program is delivered in addition to face-to-face physiotherapy. A total of 46 boys aged 6-12 years with a confirmed diagnosis of DMD will be recruited and randomly assigned to either an intervention group or a control group. Both groups will attend an 8-week center-based physiotherapy program. The intervention group will additionally use the gamified mobile exercise application at home, while the control group will receive a standard home exercise program. Participants will be evaluated before treatment, after 8 weeks, and at 6-month follow-up. The primary outcomes include physical function, endurance, and mobility. Secondary outcomes include psychosocial well-being, motivation, and therapy participation. The study intends to determine whether gamification-based telerehabilitation can increase adherence, preserve physical abilities, and support participation in children with DMD. If effective, this approach may offer a practical and accessible tool to support long-term rehabilitation needs in this population.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 46 (estimated)
- First submitted
- 18 Jan 2026
- Start date
- 8 May 2026
- Primary completion date
- 21 Dec 2026
- Lead sponsor
- Başak Çağla Arslan
- Diseases
- Duchenne muscular dystrophy
- NCT number
- NCT07368400
What you commit to
- Study type: Interventional
- Planned participants: 46
- From 8 May 2026 to the primary completion date, 21 Dec 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of any additional diagnosed neurological disorder other than, or in addition to, Duchenne muscular dystrophy.
- History of any injury and/or surgery within the last 6 months.
Other
- Any cooperation or behavioral problem that prevents completion of the assessment procedures.
- Difficulty in understanding or speaking Turkish.
Who the study is looking for
- Male child aged 6 to 12 years with a confirmed diagnosis of Duchenne muscular dystrophy (DMD) based on specialist evaluation and genetic testing.
- Vignos lower extremity classification stage 1 or 2.
- Brooke upper extremity functional classification at least stage 5.
- Score of 27 or higher on the Modified Mini-Mental Test.
- Ability to walk independently for at least 6 minutes.
- Receiving physiotherapy and rehabilitation for at least 8 sessions over a 1-month period.
- Having regular access to the internet at home.
- Parent(s) or legal guardian willing to allow the child to participate and able to read and sign the written informed consent form.
Age in the registry: 6 years to 12 years · Sex: Male · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.