NCT07370220CompletedPhase 2
Effect of Rutin on Inflammation Pathways in Ulcerative Colitis Patients
Rutin Therapy Reduces Ulcerative Colitis Disease Activity By Inhibiting The NOD-Like Receptor Protein 3 (NLRP3) Inflammasome: A Molecular Assessment in an Interventional Study.
Source: ClinicalTrials.gov · Last updated 27 Jan 2026
Brief summary (registry, in English)
This study evaluates the therapeutic role of Rutin (a plant-derived flavonoid) in reducing the severity of Ulcerative Colitis (UC). The study investigates whether Rutin can decrease intestinal inflammation and improve clinical symptoms by inhibiting the NLRP3 inflammasome signaling pathway, which is activated by oxidative stress in the colon.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 19 Jan 2026
- Start date
- Feb 2025
- Primary completion date
- May 2025
- Lead sponsor
- Benha University
- Diseases
- Ulcerative colitis
- NCT number
- NCT07370220
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 60
- From Feb 2025 to the primary completion date, May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known hypersensitivity to Rutin.
- Presence of other serious systemic diseases (e.g., malignancy, severe hepatic or renal failure).
Other
- Pregnancy or breastfeeding.
Who the study is looking for
- Diagnosis of UC confirmed by endoscopy/histology.
- Age 18 to 65 years.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Benha Faculty of Medicine Coordinator of this site? Confirm its status | Banhā | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.