NCT07370532RecruitingPhase 2
Etoricoxib in Patients With Parkinsonian Disease
Clinical Study to Evaluate Safety and Efficacy of Etoricoxib in Patients With Parkinson's Disease Treated With Conventional Treatment
Source: ClinicalTrials.gov · Last updated 8 Apr 2026
Brief summary (registry, in English)
Neuroinflammation is considered one of the most important factors contributing critically to pathophysiology of PD . Recently, high mobility group box-1 (HMGB1) protein has been encoded as a potential inflammatory biomarker in PD. HMGB1 mediates immune response mostly through endothelial cells and macrophage activation via targeting two vital cell receptors; Toll-like receptor 4 (TLR4) and advanced glycation end products (RAGE).
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 17 Jan 2026
- Start date
- 30 Jan 2026
- Primary completion date
- 10 Nov 2027
- Lead sponsor
- Ihab Elsayed Hassan
- Diseases
- Parkinson disease
- NCT number
- NCT07370532
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 60
- From 30 Jan 2026 to the primary completion date, 10 Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Alcohol and / or drug abusers.
- Patients who are currently using other anti-inflammatory drugs.
Other illness
- Patients with known allergy to the study medications
Other
- Breast feeding
- Patients with significant liver and kidney function abnormalities.
- Pregnant women and women with planned pregnancy.
Who the study is looking for
- Age ≥ 18 years.
- Both male and female will be included.
- Patients diagnosed with PD according to Unified Parkinson's Disease Rating Scale.
Age in the registry: 50 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mansoura University Coordinator of this site? Confirm its status | Al Mansurah | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.