NCT07377604Active, not recruiting
Hemoglobin Levels and Resolution Time of Diabetic Ketoacidosis in Pediatric Patients
Impact of Anemia on Time to Resolution of Diabetic Ketoacidosis and Hospital Outcomes in Children: A Single-Center Retrospective Cohort Study
Source: ClinicalTrials.gov · Last updated 30 Jan 2026
Brief summary (registry, in English)
This retrospective observational cohort study aims to evaluate the association between hemoglobin levels and the time to resolution of diabetic ketoacidosis (DKA) in pediatric patients. The primary hypothesis is that children with anemia experience a longer duration of DKA and prolonged hospitalization compared with non-anemic children. All eligible patients aged 1-18 years who were diagnosed with DKA between 01.01.2013 and 01.01.2025 at a tertiary pediatric center will be included. Clinical, laboratory, and treatment data will be collected from electronic medical records.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 13 Jan 2026
- Start date
- 11 Nov 2013
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- Aydin Adnan Menderes University
- Diseases
- Type 1 diabetes
- NCT number
- NCT07377604
What you commit to
- Study type: Observational
- Planned participants: 150
- From 11 Nov 2013 to the primary completion date, 31 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known hemoglobinopathies (e.g., thalassemia major, sickle cell disease)
Lab values
- Missing hemoglobin measurement within the predefined post-resolution window (0-24 hours)
Other
- Hyperosmolar hyperglycemic state (HHS) or mixed DKA-HHS presentation
- Evidence of active hemolysis documented in medical records (e.g., elevated lactate dehydrogenase, indirect hyperbilirubinemia, or low haptoglobin)
- Red blood cell transfusion administered before or during the DKA treatment period
Who the study is looking for
- Age between 1 and 18 years
- Diagnosis of diabetic ketoacidosis (DKA) according to ISPAD criteria
- First documented episode of DKA
- Availability of hemoglobin measurement obtained within 0-24 hours after biochemical resolution of DKA
- Availability of documented timestamps for initiation of DKA treatment and biochemical resolution
Age in the registry: 1 year to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Adnan Menderes University Coordinator of this site? Confirm its status | Aydin | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.