NCT07378228Completed
Weak Pulse at Yang and Wiry Pulse at Yin Theory
Clinical Application and Mechanistic Study of National Traditional Chinese Medicine Master Lu Fang's "Weak Pulse at Yang and Wiry Pulse at Yin" Theory in Treating Angina Pectoris of qi Deficiency and Blood Stasis Pattern Secondary to Coronary Heart Disease
Source: ClinicalTrials.gov · Last updated 30 Jan 2026
Brief summary (registry, in English)
This is a clinical study to evaluate the effectiveness and explore the possible working mechanisms of a traditional Chinese herbal formula called Yixin Powder. The study focuses on patients with stable angina pectoris (chest pain) caused by coronary heart disease (CHD), who are diagnosed with a specific Chinese medicine pattern known as "qi deficiency and blood stasis," based on the "weak pulse at yang and wiry pulse at yin" theory. The study hypothesizes that adding Yixin Powder to standard Western medication will be beneficial for these patients. To test this, participants diagnosed with this condition will be randomly assigned to one of two groups. One group will receive standard medication alone, while the other group will receive the same standard medication plus Yixin Powder. The effects of the treatments will be compared between the two groups.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 70 (actual)
- First submitted
- 21 Jan 2026
- Start date
- Jul 2023
- Primary completion date
- Jun 2024
- Lead sponsor
- Xikun Li
- Diseases
- Coronary artery disease
- NCT number
- NCT07378228
What you commit to
- Study type: Interventional
- Participants enrolled: 70
- From Jul 2023 to the primary completion date, Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Requirement for long-term use of medications that could interfere with study outcomes;
Other illness
- Uncontrolled severe hypertension (BP ≥180/110 mmHg);
- Severe comorbid conditions involving major organs or systems, including heart, brain, liver, or kidneys;
- Known allergy to, or intolerance of, any of the study medications; (3) Presence of psychiatric disorders;
- Coexisting infectious diseases.
Who the study is looking for
- Diagnosis of CHD-induced stable angina pectoris according to Western medicine diagnostic criteria；
- Diagnosis of qi deficiency and blood stasis pattern according to TCM pattern differentiation;
- Age between 40 and 70 years, regardless of sex;
- Stable vital signs and normal liver and renal function before enrollment;
- Angina severity graded between I and III;
- Voluntary participation with signed informed consent.
Age in the registry: 40 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Xikun Li Coordinator of this site? Confirm its status | Harbin | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.