NCT07378605Not yet recruiting
Effect of Intraoperative Salbutamol Administration on Mechanical Power and Respiratory Mechanics in Obese Patients Undergoing Laparoscopic Bariatric Surgery
Source: ClinicalTrials.gov · Last updated 30 Jan 2026
Brief summary (registry, in English)
The primary objective of this study is to evaluate the effect of intraoperative salbutamol administration on mechanical power in obese patients undergoing laparoscopic bariatric surgery under general anesthesia. Mechanical power will be measured at predefined intraoperative time points (T0, T1, and T2), and changes over time will be compared to determine the impact of salbutamol on the overall energy delivered to the respiratory system during mechanical ventilation. Secondary objectives include the assessment of intraoperative respiratory mechanics, including peak airway pressure (Ppeak), plateau pressure (Pplat), driving pressure (Pdrive), airway resistance (Raw), and lung compliance, as well as gas exchange parameters (SpO₂, EtCO₂) and hemodynamic variables (mean arterial pressure). Postoperative pulmonary outcomes will be evaluated using the Melbourne Group Scale (MGS), with a score greater than 4 indicating the presence of postoperative pulmonary complications. The study aims to investigate whether improvement in intraoperative mechanical power and respiratory mechanics is associated with a reduction in postoperative pulmonary complications in this high-risk population.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 66 (estimated)
- First submitted
- 26 Dec 2025
- Start date
- 1 Jan 2026
- Primary completion date
- 1 Mar 2026
- Lead sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
- Diseases
- Obesity
- NCT number
- NCT07378605
What you commit to
- Study type: Interventional
- Planned participants: 66
- From 1 Jan 2026 to the primary completion date, 1 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Emergency surgery
- Use of β-agonists or bronchodilators within 24 hours prior to surgery
Other illness
- Known allergy or contraindication to salbutamol
- Severe cardiovascular disease (e.g., recent MI, uncontrolled arrhythmia)
- Pre-existing severe pulmonary disease (e.g., severe COPD, asthma exacerbation)
Other
- Pregnancy or lactation
- Patients with inability to provide informed consent
- \-
Who the study is looking for
- Age: 18-65 years
- BMI ≥35 kg/m² (candidates for obesity surgery)
- Scheduled for elective laparoscopic bariatric surgery
- ASA physical status I-III
- Signed informed consent
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Health Sciences University Gazi Yaşargil Training and Research Hospital Coordinator of this site? Confirm its status | Kayapınar | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.