NCT07379658Not yet recruiting
Long-Acting Injectable HIV PrEP PROs
Improving HIV Prevention Outcomes: Insights on Long-Acting Injectable (LAI) HIV Pre-Exposure Prophylaxis (PrEP) Patient-Reported Medication Preferences, Adherence, and Clinical Outcomes (IMPACT) in a Southern US State
Source: ClinicalTrials.gov · Last updated 30 Jan 2026
Brief summary (registry, in English)
The goal of this observational study is to learn about the real world effectiveness, patient satisfaction and clinical outcomes of LAI PrEP with lenacapavir (LEN) versus cabotegravir (CAB) through surveys and interviews. Participants receiving or initiating LAI PrEP part of their regular medical care will complete surveys and interviews at three study visits over the course of 12 months.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 128 (estimated)
- First submitted
- 5 Jan 2026
- Start date
- Jan 2026
- Primary completion date
- Jan 2028
- Lead sponsor
- Anupama Raghuram MD
- Diseases
- HIV
- NCT number
- NCT07379658
What you commit to
- Study type: Observational
- Planned participants: 128
- From Jan 2026 to the primary completion date, Jan 2028
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- HIV diagnosis prior to enrollment
- Currently on oral PrEP with no plans to switch to LAI PrEP
Other
- Hypersensitivities to LEN or CAB
- Pregnant or planning to become pregnant
- PI discretion
Who the study is looking for
- Adults aged 18 and older
- Deemed eligible for HIV PrEP per healthcare provider
- Receiving or initiating LAI PrEP, defined as:
- Current use of CAB or LEN LAI PrEP at study entry
- Initiation of either CAB or LEN LAI PrEP within 30 days of study enrollment
- Receiving PrEP services in Louisville, KY
- Able to provide informed consent and complete study assessments
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Norton Healthcare Coordinator of this site? Confirm its status | Louisville | United States | Unknown status |
| University of Louisville, School of Public Health and Information Sciences Coordinator of this site? Confirm its status | Louisville | United States | Unknown status |
| University of Louisville, Kent School of Social Work Coordinator of this site? Confirm its status | Louisville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.