NCT07380464Completed
A New Classification System for Lymph Nodes in Colon Cancer: The Prognostic Significance of the Anatomical Distribution of Metastatic Lymph Nodes and the Number of Tumor Deposits
Source: ClinicalTrials.gov · Last updated 2 Feb 2026
Brief summary (registry, in English)
This study aims to investigate the prognostic significance of LNM distribution and establish a new classification system integrating both nodal quantity and anatomical location.The main question it aims to answer is: Does the new N staging based on lymph node metastasis patterns and cancer nodules provide a more accurate prediction of the prognosis of colon cancer patients compared to the AJCC N staging? The relevant clinical characteristics, treatment processes, postoperative pathological data and post-discharge prognosis information of the enrolled patients were collected through the follow-up offices and the medical record system. The data were analyzed. The main research endpoints were: overall survival (the time between the initial surgery and death or the last follow-up); disease-free survival (the time between the initial surgery and disease metastasis, recurrence or death).
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1500 (actual)
- First submitted
- 22 Jan 2026
- Start date
- 5 Mar 2010
- Primary completion date
- 31 Jul 2025
- Lead sponsor
- Cai Zerong
- Diseases
- Colorectal cancer, Childhood cancers
- NCT number
- NCT07380464
What you commit to
- Study type: Observational
- Participants enrolled: 1500
- From 5 Mar 2010 to the primary completion date, 31 Jul 2025
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Multiple primary cancers or concurrent malignancies in other sites.
Other illness
- Intraoperative or postoperative pathology confirming non-malignant tumors (including carcinoma in Tis).
Who the study is looking for
- Definite diagnosis of primary colon adenocarcinoma via auxiliary examination or pathology.
- No distant metastasis (M0) confirmed by preoperative imaging or intraoperative findings.
- No prior neoadjuvant therapy (including chemotherapy, radiotherapy, immunotherapy, or targeted therapy).
- Underwent initial radical resection for colon cancer.
- Available data on lymph node counts for all three stations.
Sex: All · Does not accept healthy volunteers
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