NCT07381972RecruitingPhase 3
Photodynamic Therapy Associated With Sonodynamic Therapy for the Treatment of Nodular Basal Cell Carcinoma
Optimization of Photodynamic Therapy Through the Association With Sonodynamic Therapy for the Treatment of Nodular Basal Cell Carcinoma
Source: ClinicalTrials.gov · Last updated 2 Feb 2026
Brief summary (registry, in English)
Evaluation of a therapeutic protocol based on the combination of photodynamic therapy and sonodynamic therapy, referred to as sonophotodynamic therapy. Since this new protocol is applied in a single day, it is called the single-visit Sono-PDT protocol. This protocol will be used for the treatment of nodular basal cell carcinoma lesions.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 142 (estimated)
- First submitted
- 13 Jan 2026
- Start date
- 24 Nov 2025
- Primary completion date
- 31 Aug 2026
- Lead sponsor
- University of Sao Paulo
- Diseases
- Melanoma
- NCT number
- NCT07381972
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 142
- From 24 Nov 2025 to the primary completion date, 31 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known hypersensitivity or allergy to methyl aminolevulinate (MAL) or any excipients of the study medication.
- Porphyria or other disorders of porphyrin metabolism.
- Presence of photosensitive diseases, including lupus erythematosus.
- Any condition that, in the investigator's opinion, would interfere with study participation or safety.
Other
- Nodular basal cell carcinoma lesions \>1.0 cm in diameter.
- Histological subtypes of infiltrative basal cell carcinoma, including micronodular, infiltrative, sclerodermiform (morpheaform), plano-cicatricial, or terebrant subtypes.
- Pregnant or breastfeeding women.
- Women of childbearing potential not using an acceptable method of contraception.
Who the study is looking for
- Adults of both sexes, aged 18 years and older.
- Histologically confirmed nodular basal cell carcinoma with lesion diameter ≤1.0 cm.
- Participants with multiple lesions may be included, provided that each lesion meets all inclusion criteria.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Amaral Carvalho Coordinator of this site? Confirm its status | Jaú | Brazil | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.