NCT07382089Completed
Effect of Oral Hygiene Care on Prevention of Aspiration Pneumonia Among Hospitalized Stroke Patients
Effect of Oral Hygiene Care on Aspiration Pneumonia Among Hospitalized Stroke Patients: A Quasi-Experimental Study With Historical Controls
Source: ClinicalTrials.gov · Last updated 2 Feb 2026
Brief summary (registry, in English)
Aspiration pneumonia is a common and serious complication among hospitalized patients with stroke. Poor oral hygiene can increase the risk of aspiration pneumonia by promoting bacterial colonization of the oral cavity. This study evaluated whether implementing a structured oral hygiene care protocol during hospitalization could reduce the incidence of aspiration pneumonia among stroke patients. In this non-randomized, quasi-experimental study, patients admitted after implementation of an oral hygiene care protocol received structured oral care delivered by trained nursing staff, while patients admitted prior to implementation served as historical controls and received standard care. The primary outcome was the occurrence of aspiration pneumonia during hospitalization. The findings of this study aim to inform simple, low-cost preventive strategies that may improve clinical outcomes for hospitalized stroke patients, particularly in resource-limited settings.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 90 (actual)
- First submitted
- 26 Jan 2026
- Start date
- 1 May 2023
- Primary completion date
- 30 Jan 2024
- Lead sponsor
- Addis Ababa University
- Diseases
- Stroke
- NCT number
- NCT07382089
What you commit to
- Study type: Interventional
- Participants enrolled: 90
- From 1 May 2023 to the primary completion date, 30 Jan 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with facial or oral conditions precluding oral hygiene care
Other
- Patients with active pneumonia at the time of hospital admission
- Patients who were intubated or mechanically ventilated at admission
- Patients discharged or deceased within 24 hours of admission
Who the study is looking for
- Adults aged 18 years or older
- Hospitalized patients with a confirmed diagnosis of acute stroke (ischemic or hemorrhagic)
- Admission to the stroke unit or medical ward during the study period
- Ability to receive oral care as part of routine nursing care
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tikur Anbessa Specialized Hospital, Addis Ababa University Coordinator of this site? Confirm its status | Addis Ababa | Ethiopia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.