NCT07382674Recruiting
Zesty Exercise System for Therapeutic Engagement
Source: ClinicalTrials.gov · Last updated 26 May 2026
Brief summary (registry, in English)
This study will evaluate exercise delivered through the Zesty Exercise System for Therapeutic Engagement (ZEST-E) for people with Parkinson's disease when sessions are monitored either in person or remotely. Participants will complete robot-guided exercise three times per week for three weeks. The study will assess feasibility, retention, safety, acceptability, and tolerability of remotely monitored ZEST-E and will measure changes in functional performance using the Standing Forward Reach test and the 30-Second Chair Stand test. These outcomes reflect range of motion and lower-body strength targeted by the exercise program.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 46 (estimated)
- First submitted
- 27 Jan 2026
- Start date
- 16 Mar 2026
- Primary completion date
- Feb 2028
- Lead sponsor
- Emory University
- Diseases
- Parkinson disease
- NCT number
- NCT07382674
What you commit to
- Study type: Interventional
- Planned participants: 46
- From 16 Mar 2026 to the primary completion date, Feb 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- On medications that could adversely affect cognition, e.g.: antipsychotics, opioids, stimulants, chemotherapy;
Other illness
- Acute medical illness requiring hospitalization;
- Uncontrolled congestive heart failure;
- History of stroke in the past three years;
- Medical or physical conditions that would preclude participation (e.g., severe arthritis or mobility problems, uncontrolled hypertension or diabetes, renal failure, history of angina with activity);
- Psychotic disorders;
- Confounding neurologic conditions (e.g., active central nervous system opportunistic infections, seizure disorders, head injury with loss of consciousness \>30 minutes, intracranial neoplasms, stroke with neurological or neuropsychiatric sequelae);
- Substance Use Disorder, Major Depressive and Generalized Anxiety Disorders within six months of evaluation;
Age
- Under 40 years old;
Other
- Inability to perform study procedures;
- Hohn \& Yahr \> 3
- MoCA \<17
Who the study is looking for
- -Older adults with mild to moderate PD.
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Emory University, 57 Executive Park S NE, Ste 200 Coordinator of this site? Confirm its status | Atlanta | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.