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NCT07383454Not yet recruiting

Lung Cancer Screening in Population Who Had Never Smoked

Lung Cancer Screening in Population Who Had Never Smoked and the Validation of Lung Cancer Risk Prediction Model

Source: ClinicalTrials.gov · Last updated 3 Feb 2026

Brief summary (registry, in English)

Study design: prospective, single arm. Objectives: survey lung cancer detection rate of low-dose computed tomography (LDCT) screening in individuals who had never smoked. Participants will undergo questionnaires, and collecting specimens including blood, urine, and medical informations including results of pulmonary function tests, and LDCT screening upon inclusion. The participants will be followed up according to current standards of clinical practice.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
2500 (estimated)
First submitted
26 Jan 2026
Start date
1 Feb 2026
Primary completion date
Dec 2030
Lead sponsor
Chung Shan Medical University
Diseases
Lung cancer
NCT number
NCT07383454

What you commit to

  • Study type: Interventional
  • Planned participants: 2500
  • From 1 Feb 2026 to the primary completion date, Dec 2030
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of lung cancer, or a diagnosis of any malignancy other than skin cancer or cervical carcinoma in situ within the past five years.

Other

  • Undergoing chest computed tomography (CT) scans within the past 18 months.
  • Unexplained hemoptysis within the past one month.
  • Unexplained weight loss exceeding 6 kilograms within the past one year.
  • Pregnancy.

Who the study is looking for

  • Individuals with no history of smoking.
  • Aged 40 to 80 years.
  • Willing to provide written informed consent and complete questionnaire assessments.
  • After undergoing examinations, willing to provide relevant biological information, including but not limited to: blood samples, urine samples, pulmonary function test results, imaging data, and tissue specimens obtained from invasive biopsies or surgical procedures (if applicable).

Age in the registry: 40 years to 80 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.