NCT07383883Recruiting
Multimodal Tongue-Pulse Information Fusion for Syndrome Diagnosis and Cohort Study in Children With Asthma
Source: ClinicalTrials.gov · Last updated 10 Mar 2026
Brief summary (registry, in English)
Asthma is one of the most prevalent chronic respiratory diseases in children, and accurate phenotyping and disease monitoring remain challenging in routine clinical practice. This observational cohort study aims to investigate the clinical value of multimodal tongue and pulse information in the syndrome diagnosis and phenotypic characterization of pediatric asthma. Children aged 5-18 years with a confirmed diagnosis of asthma will be enrolled at Shanghai Children's Medical Center and followed in routine outpatient care. Standardized tongue images and pulse wave data will be collected using validated acquisition devices during visits when lung function testing is performed. Quantitative features extracted from tongue and pulse data will be integrated with clinical information, including asthma stage, lung function parameters, eosinophil counts, allergic sensitization status, and Asthma Control Questionnaire-5 (ACQ-5) scores. The primary objective is to evaluate the associations between tongue-pulse multimodal features and asthma clinical stages and pulmonary function. Secondary objectives include exploring their relationships with airway inflammation and asthma control status. This study seeks to establish a non-invasive, objective, and quantifiable approach to asthma phenotyping, providing evidence for integrating traditional diagnostic features with modern clinical data to support precision management of pediatric asthma.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 14 Dec 2025
- Start date
- 1 Feb 2026
- Primary completion date
- 31 Jan 2028
- Lead sponsor
- Shanghai Children's Medical Center
- Diseases
- Asthma
- NCT number
- NCT07383883
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 1 Feb 2026 to the primary completion date, 31 Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of other chronic respiratory diseases (e.g., cystic fibrosis, bronchiectasis, primary ciliary dyskinesia).
- Congenital cardiopulmonary malformations or significant cardiovascular disease.
- Acute respiratory infection or fever at the time of data collection.
- Severe systemic diseases or immunodeficiency that may affect study participation.
Other
- Inability to comply with study procedures or incomplete clinical data.
Who the study is looking for
- Children aged 5 to 18 years.
- Clinically diagnosed asthma according to established pediatric asthma guidelines.
- Receiving routine outpatient follow-up at Shanghai Children's Medical Center.
- Able to cooperate with tongue image acquisition and pulse wave data collection.
- Able to perform pulmonary function testing when clinically indicated.
- Written informed consent obtained from parents or legal guardians, with assent from the child when appropriate.
Age in the registry: 5 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shanghai Children's Medical Center Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.