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NCT07384143Recruiting

Cognitive Recovery Via Sensor-based Robotic Upper Limb Rehabilitation in Neurological Disorders

Exploring Cognitive Recovery: the Impact of Sensor-based Robotic Rehabilitation in Neurological and Neurodegenerative Disorders

Source: ClinicalTrials.gov · Last updated 3 Feb 2026

Brief summary (registry, in English)

The goal of this clinical trial is to learn if sensor-based robotic upper limb rehabilitation can improve cognitive and motor functions in adults with neurological and neurodegenerative disorders, including Parkinson's disease, multiple sclerosis, and stroke. The main questions it aims to answer are: Does sensor-based robotic rehabilitation improve cognitive functions such as attention, memory, and executive functions? Does this rehabilitation lead to better motor recovery and daily functioning compared to conventional therapy? Researchers will compare the experimental group receiving robotic rehabilitation with cognitive tasks to the control group receiving conventional therapy to see if the robotic approach leads to greater improvements in both cognitive and motor outcomes. Participants will: Receive upper limb rehabilitation using robotic devices and virtual reality-based exercises or conventional therapy Complete a series of neuropsychological assessments before and after the intervention to measure cognitive changes Complete motor function tests before and after the intervention to evaluate physical improvements Participate in 25 training sessions, 2-3 times per week, each lasting 60 minutes

Status (registry)
Recruiting
Study type
Interventional
Enrollment
189 (estimated)
First submitted
30 Sept 2025
Start date
11 Feb 2025
Primary completion date
11 Feb 2030
Lead sponsor
IRCCS Centro Neurolesi Bonino Pulejo
NCT number
NCT07384143

What you commit to

  • Study type: Interventional
  • Planned participants: 189
  • From 11 Feb 2025 to the primary completion date, 11 Feb 2030
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Severe cognitive disorders
  • Behavioral disorders
  • Sensory disorders

Who the study is looking for

  • Age 18-75 years;
  • FMA-UL 0-31: eligible for exoskeletons and robotic devices with high support. (Armeo Power, Amadeo, Motore)
  • FMA-UL 32-47: eligible for end-effectors with medium support. (Armeo Spring, Hand Tutor, Diego)
  • FMA-UL 48-52: eligible for sensor-based with low support. (Pablo, Diego, Armeo Senso)
  • MoCA: ≤ 20

Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
IRCCS Centro Neurolesi Bonino Pulejo
Coordinator of this site? Confirm its status
MessinaItalyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.