NCT07386015Recruiting
Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)
FREEZE-Path Cohort: Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)
Source: ClinicalTrials.gov · Last updated 10 Mar 2026
Brief summary (registry, in English)
This study is a prospective, multicenter, observational cohort (patient registry) designed to better understand freezing of gait (FOG), a disabling walking problem that can occur in Parkinson's disease and other related neurological conditions.The purpose of this registry is to collect long-term clinical information from patients with freezing of gait or gait and balance problems, and to explore how different causes of FOG are related to symptoms, walking patterns, falls, disease progression, and outcomes over time. The study will include participants with Parkinson's disease and other conditions associated with freezing of gait.Participants will receive standard medical care as determined by their treating physicians. No experimental drugs or study-related treatments will be assigned as part of this registry. Clinical information will be collected during routine visits and follow-up assessments, including questionnaires, walking and balance evaluations, video recordings, and other commonly used clinical tests.The information collected in this study may help improve the understanding of freezing of gait, support better risk assessment for falls, and guide future research and clinical management strategies for patients with gait and balance disorders.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 700 (estimated)
- First submitted
- 24 Dec 2025
- Start date
- 28 Feb 2026
- Primary completion date
- 31 Dec 2029
- Lead sponsor
- Tianjin Huanhu Hospital
- Diseases
- Parkinson disease
- NCT number
- NCT07386015
What you commit to
- Study type: Observational
- Planned participants: 700
- From 28 Feb 2026 to the primary completion date, 31 Dec 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe dementia (Mini-Mental State Examination score \< 10)
- Severe psychiatric disorders interfering with study participation
- Severe cardiopulmonary, musculoskeletal, or other medical conditions significantly affecting gait safety
- Stroke, fracture, or other major medical events within the past 3 months
Other
- Inability to comply with follow-up procedures
- Refusal of video or speech data collection
Who the study is looking for
- Age 30-85 years
- Presence of freezing of gait or non-freezing gait or balance impairment
- Diagnosis of Parkinson's disease or related parkinsonian disorders according to established international criteria (including PD, PSP, MSA, DLB, CBD, vascular parkinsonism, or idiopathic normal pressure hydrocephalus)
- Ability to complete gait and balance assessment tasks independently or with assistance
- Ability and willingness to provide written informed consent
Age in the registry: 30 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tianjin Huanhu Hospital Coordinator of this site? Confirm its status | Tianjin | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.