Sign in

NCT07386717Completed

Upadacitinib Versus IL-17 Inhibitors in Patients With Psoriatic Arthritis

Upadacitinib Versus IL-17 Inhibitors in Patients With Psoriatic Arthritis: A Cohort Study

Source: ClinicalTrials.gov · Last updated 4 Feb 2026

Brief summary (registry, in English)

Psoriatic arthritis (PsA) is a chronic inflammatory disease with heterogeneous musculoskeletal and dermatologic manifestations, leading to significant functional impairment and reduced quality of life. Although targeted therapies such as Janus kinase inhibitors and interleukin-17 inhibitors have demonstrated efficacy in randomized controlled trials, real-world comparative evidence between these treatment strategies remains limited. This observational cohort study aims to compare the real-world effectiveness and safety of upadacitinib and interleukin-17 inhibitors in patients with PsA over a 24-week follow-up period. By evaluating clinical outcomes under routine clinical practice conditions, this study seeks to provide evidence to support individualized treatment selection in PsA management.

Status (registry)
Completed
Study type
Observational
Enrollment
70 (actual)
First submitted
27 Jan 2026
Start date
1 Jan 2024
Primary completion date
31 Dec 2025
Lead sponsor
Peking University First Hospital
NCT number
NCT07386717

What you commit to

  • Study type: Observational
  • Participants enrolled: 70
  • From 1 Jan 2024 to the primary completion date, 31 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of malignancy or severe uncontrolled infection

Other

  • Diagnosis of other inflammatory arthritides
  • Incomplete clinical data preventing outcome assessment

Who the study is looking for

  • Age ≥ 18 years
  • Diagnosis of psoriatic arthritis according to established classification criteria
  • Treatment with upadacitinib or an interleukin-17 inhibitor at baseline
  • Availability of baseline and follow-up clinical data over 24 weeks

Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Peking University First Hospital
Coordinator of this site? Confirm its status
BeijingChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.