NCT07386834Not yet recruiting
Large-Scale Study of Oro-esophageal Feeding Versus Nasogastric Feeding for Swallowing Function and Airway Protection
The Effect of Oro-esophageal Versus Nasogastric Feeding for Stroke Patients With Dysphagia: A Multicenter Randomized Controlled Large-Scale Study
Source: ClinicalTrials.gov · Last updated 11 Mar 2026
Brief summary (registry, in English)
This is a randomized controlled trial involving patients with ischemic stroke and dysphagia. The aim of this study is to explore the recovery speed and therapeutic effect of oro-esophageal feeding compared with nasogastric feeding on swallowing function. This study mainly addresses the following two research questions: 1. Whether oro-esophageal feeding improves swallowing function more rapidly and effectively than nasogastric tube feeding. 2. Whether oro-esophageal feeding is non-inferior to nasogastric tube feeding in terms of safety.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 422 (estimated)
- First submitted
- 26 Jan 2026
- Start date
- Mar 2026
- Primary completion date
- Mar 2027
- Lead sponsor
- Zeng Changhao
- Diseases
- Stroke
- NCT number
- NCT07386834
What you commit to
- Study type: Interventional
- Planned participants: 422
- From Mar 2026 to the primary completion date, Mar 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Dysphagia that might be caused by other diseases or structural abnormalities.
- Complicated with severe liver and kidney failure, tumors, or hematological disorders.
Other
- Contraindications for tube feeding.
- Pregnancy or breast feeding.
- Anticipated discharge from the hospital or transfer to another hospital within two week.
Who the study is looking for
- Age\>18 years.
- First stroke
- Disease duration less than one month.
- Ischemic stroke.
- Patients who need enteral feeding.
- Dysphagia confirmed by imaging Study.
- Clear consciousness.
- Stable vital signs.
- With informed consent and participants who understand and agree to comply with planned study procedures.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.