NCT07387432Recruiting
Role of Exercise in PRISm and Subsequent Development of COPD
Role of Exercise in Functional Capacity of Smokers and Subsequent Development of Chronic Obstructive Pulmonary Disease
Source: ClinicalTrials.gov · Last updated 6 Mar 2026
Brief summary (registry, in English)
Preserved Ratio Impaired Spirometry (PRISm) describes individual with spirometry findings of forced expiratory volume (FEV1) and forced vital capacity (FVC) ratio greater than 0.7 but with the FEV1 less than 80% predicted. While the spirometry findings of individuals with PRISm can be transited into obstructive pattern, remains at PRISm or become normal spirometry, limited evidence is on the role of exercise in the course of PRISm. This study aims to investigate the role of exercise, namely exercise with telehealth and walking exercise, together with smoking cessation advice, would alter the clinical course of PRISm.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- First submitted
- 27 Jan 2026
- Start date
- 14 Jul 2025
- Primary completion date
- Jan 2027
- Lead sponsor
- The University of Hong Kong
- Diseases
- COPD
- NCT number
- NCT07387432
What you commit to
- Study type: Interventional
- Planned participants: 90
- From 14 Jul 2025 to the primary completion date, Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Age below 18
Other
- Non-smoker
- Spirometry does not show PRISm/ unable to perform spirometry
- Requires assistance for walking
- Unable to give informed consent
Who the study is looking for
- Age 18 or above
- Smoker/ ex-smoker
- Spirometry shows PRISm, with FEV1/FVC \>= 0.7 and FEV1 \<80% predicted
- Ambulatory to walk
- Able to give informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The University of Hong Kong, Queen Mary Hospital Coordinator of this site? Confirm its status | Hong Kong | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.