NCT07389720Recruiting
Characterization of (A)Typical Sensorimotor Pathways in Individuals With Autism
Source: ClinicalTrials.gov · Last updated 5 Feb 2026
Brief summary (registry, in English)
The goal of this interventional study is to understand whether sensorimotor skills could represent an endophenotype for autism, i.e. a specific class of biomarkers that bridges the gap between biological components of a condition and the behavioral/clinical dimensions. Motor and sensory differences are often observed in people with autism and may appear early in development or be shared among family members. The study will address three main questions: * What are the developmental effects of early differences in motor and sensory skills? * Are motor and sensory abilities influenced by family relationships? * Can studying motor and sensory differences in autism help researchers better understand the biological mechanisms underlying the condition? This study is structured in three topic-oriented work packages (WPs): WP1, a longitudinal assessment of sensorimotor skills as early predictors of later social characteristics in a mixed sample of infant siblings of autistic children (at elevated likelihood of autism) or with typical familial likelihood (no first-degree relatives with autism) (Q1); WP2, a cross-sectional investigation of sensorimotor abilities in autistic children and their parents as compared with typically developing children and their parents (Q2); and WP3, a dense-phenotyping approach to establish, within individuals, associations between traits across behavioral, neural, and molecular levels.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 300 (estimated)
- First submitted
- 21 Jan 2026
- Start date
- 21 May 2024
- Primary completion date
- Dec 2026
- Lead sponsor
- IRCCS Eugenio Medea
- Diseases
- Autism
- NCT number
- NCT07389720
What you commit to
- Study type: Interventional
- Planned participants: 300
- From 21 May 2024 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current use of medications and/or psychotropic drugs.
Other illness
- Presence of medical and/or neurological conditions of clinical significance, including epilepsy.
- Presence of dysmorphic syndromes or known genetic syndromes.
Who the study is looking for
- children aged 2 to 12 years (both autistic and typically developing)
- Clinical diagnosis of Autism Spectrum Disorder based on clinical judgment according to DSM-5 criteria (for the autism group).
- being parents of the enrolled children (both autistic and typically developing)
- infants younger than 24 months of age with a first-degree family member with a clinical diagnosis of Autism Spectrum Disorder.
Age in the registry: 1 year to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IRCCS E. Medea Coordinator of this site? Confirm its status | Bosisio Parini | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.