NCT07390669Active, not recruiting
OptimAIR: Towards Right Care in Asthma Through Point-of-care Phenotyping, Guideline-based Assessment and Management Optimalisation Using the AsthmaOptimiser in Primary Care
Source: ClinicalTrials.gov · Last updated 5 Feb 2026
Brief summary (registry, in English)
Asthma is mainly managed in primary care, yet disease control remains suboptimal. Many patients experience ongoing symptoms, exacerbations, and frequent short-acting β₂-agonist use, while underestimating the severity of their condition. Approximately 40% of patients have uncontrolled asthma based on Asthma Control Questionnaire scores. This highlights the need for structured assessment of asthma control, risk factors, inhaler technique, and alignment of treatment with international guidelines. Structured asthma reviews and digital support tools may help optimize and personalize asthma management, particularly for patients at increased risk of exacerbations. Novel risk prediction tools using biomarkers such as FeNO and blood eosinophils show promise but are not yet routinely used in primary care. This study aims to assess asthma control, identify patients at higher risk of exacerbations, and explore opportunities for management optimization in primary care. In addition, it supports the development of a longitudinal respiratory registry to facilitate clinical research and participation in future clinical trials.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 746 (actual)
- First submitted
- 15 Jan 2026
- Start date
- 1 May 2025
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- General Practitioners Research Institute
- Diseases
- Asthma
- NCT number
- NCT07390669
What you commit to
- Study type: Interventional
- Participants enrolled: 746
- From 1 May 2025 to the primary completion date, 1 Jul 2026
- 3 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Other significant respiratory disease than asthma
Other
- Well controlled asthma, defined as ACQ-6 score ≤ 0.75 and normal oscillometry (ALDS result: "normal lung function")
- Not able to understand the patient information sheet and informed consent form
Who the study is looking for
- Aged 18 years or older
- Documented physician diagnosis of asthma
- Treated with ICS+LABA
- 1 or more exacerbation(s) requiring oral or systemic corticosteroids for at least 3 days or hospital admission, or emergency room visit within 12 months prior to the OptimAIR study visit
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| - Coordinator of this site? Confirm its status | Buenos Aires | Argentina | Unknown status |
| - Coordinator of this site? Confirm its status | Santiago | Chile | Unknown status |
| - Coordinator of this site? Confirm its status | Palma de Mallorca | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.