NCT07394270Not yet recruitingPhase 2
Effect of Add-on L-Arginine Therapy on Heart Failure Patients
Effect of Add-on L-Arginine Therapy on Clinical Outcome of Heart Failure Patients: A Randomized- Controlled Trial
Source: ClinicalTrials.gov · Last updated 6 Feb 2026
Brief summary (registry, in English)
Heart failure is considered one of the greatest challenges globally. There are various treatment strategies for heart failure. L-Arginine is an amino acid that was found to have beneficial effect on vasculature. This study aims to study the benefits and side effects of using L-arginine on the patients with ejection fraction \<40%
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- First submitted
- 23 Dec 2025
- Start date
- Feb 2026
- Primary completion date
- Mar 2027
- Lead sponsor
- German University in Cairo
- Diseases
- Heart failure
- NCT number
- NCT07394270
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 200
- From Feb 2026 to the primary completion date, Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with a history of sensitivity to L-Arginine or any of the excipients
- Acute heart failure patients
- Patients with active herpes disease
Other
- Patients with implantable cardioverter-defibrillator
- Pregnant or lactating fmeales
- Patients use L-arginine supplementation.
Who the study is looking for
- Patients with EF \<40%
- eGFR \>30 mL/min/1.73 m2
- Stable patients
- Capable and willing to provide written consent
Age in the registry: 19 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ain Shams University Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.