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NCT07394413Not yet recruiting

Surgical Handling of Fertility-preserving Treatments for Cervical Adenocarcinomas

Source: ClinicalTrials.gov · Last updated 6 Feb 2026

Brief summary (registry, in English)

Despite a growing body of literature on the subject, there is still uncertainty regarding direct comparisons between different conservative surgical techniques for cervical adenocarcinomas. In particular, it remains unclear whether fertility-sparing surgery for cervical adenocarcinomas - characterized by skip lesions - can ensure optimal disease control while achieving adequate obstetric outcomes. For this reason, a systematic review and meta-analysis of the literature, along with an analysis of our center's data, is warranted. This approach will allow a critical, comparative evaluation of the efficacy of the different techniques (conization, simple trachelectomy, and radical trachelectomy) and the identification of prognostic factors to guide therapeutic choice.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
26 Jan 2026
Start date
1 Feb 2026
Primary completion date
1 Feb 2027
Lead sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
NCT number
NCT07394413

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From 1 Feb 2026 to the primary completion date, 1 Feb 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Undergoing radical surgery

Other

  • Histotypes other than cervical adenocarcinoma
  • Follow-up less than 12 months

Who the study is looking for

  • Adult women of reproductive age with a diagnosis of cervical adenocarcinoma
  • Undergoing fertility-sparing surgery
  • Minimum 12-month follow-up
  • Signed informed consent

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coordinator of this site? Confirm its status
RomaItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.