NCT07395531Not yet recruitingPhase 3
Effect of Repetitive Bihemispheric Anodal Transcranial Direct Current Stimulation on Motor Function of Patients With Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 9 Feb 2026
Brief summary (registry, in English)
Dopaminergic medications and Deep Brain Stimulation (DBS) are the current standards interventions for Parkinson's Disease. Pharmacotherapy with dopaminergic drugs leads to partial improvement in motor functions of patients. Invasive therapies like DBS have as yet limited availability and accessibility, with risk of adverse events as well. Non invasive therapies like Transcranial Direct Current Stimulation (tDCS) are currently increasingly being probed for their therapeutic value, in view of their safety, portability and convenience of administration. Improvement in motor function immediately after a single session of tDCS has been observed. The effect of single simulation is not sustained beyond a few days. Only few studies with varied sites of stimulation have evaluated the effect of repetitive tDCS on motor function improvement in patients with Parkinson's Disease, with conflicting results. There is an unmet need to probe the utility of repetitive tDCS on motor function of patients with Parkinson's Disease. We aim to probe the effect of repetitive tDCS of dorsolateral prefrontal cortex and M1 cortex on motor function in patients with Parkinson's Disease (Hoehn and Yahr stage 2 to 4).
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 25 Jan 2026
- Start date
- 1 Feb 2026
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Dr. Ram Manohar Lohia Hospital
- Diseases
- Parkinson disease
- NCT number
- NCT07395531
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 30
- From 1 Feb 2026 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with skull defect due to surgery e.g. craniectomy
Other illness
- Patients with other confounding neurological and psychiatric disorders.
- Patients with a history of deep brain stimulation.
- Patients with history of seizures.
- Patients with scalp condition likely to obstruct application of electrodes.
Other
- The presence of metal objects or stimulators in the head.
Who the study is looking for
- Patients fulfilling the Movement Disorder Society (MDS) clinical diagnostic criteria for Parkinson's disease.
- Patients with Hoehn \& Yahr stages 2-4 Parkinson's disease.
- Patients maintained on stable medical regimen for at least 1 month before entering the study.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital Coordinator of this site? Confirm its status | New Delhi | India | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.