NCT07396402Not yet recruiting
SCUBE Proteins in Polycystic Ovary Syndrome (IPSOS)
Study of Scube-1 and Scube-3 in Polycystic Ovary Syndrome (PCOS) and Their Possible Use as Inflammatory Markers and as a Link Between PCOS and Cardiovascular Events.
Source: ClinicalTrials.gov · Last updated 9 Feb 2026
Brief summary (registry, in English)
This study investigates circulating levels of SCUBE-1 and SCUBE-3 proteins in women with polycystic ovary syndrome (PCOS) compared with healthy controls. Differences between normoinsulinemic and hyperinsulinemic PCOS subgroups will be evaluated, as well as correlations with clinical and metabolic parameters related to inflammation and cardiovascular risk.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 56 (estimated)
- First submitted
- 2 Feb 2026
- Start date
- 15 Jan 2026
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- NCT number
- NCT07396402
What you commit to
- Study type: Interventional
- Planned participants: 56
- From 15 Jan 2026 to the primary completion date, 1 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of cardiovascular disease
- Hypertension
- Significant hepatic or renal disease
- Other endocrine disorders
- Neoplastic diseases
- Psychiatric disorders
- Autoimmune diseases
Lab values
- Diabetes mellitus or impaired glucose tolerance
Other
- Pregnancy
- Shift work
- Obesity
- Refusal to sign informed consent
Who the study is looking for
- Female subjects aged 18-35 years
- Diagnosis of polycystic ovary syndrome (normoinsulinemic or hyperinsulinemic)
- Availability of basal hormonal evaluation and oral glucose tolerance test
- Healthy women for control group
- Written informed consent
Age in the registry: 18 years to 35 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS Coordinator of this site? Confirm its status | Roma | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.