NCT07397715Recruiting

Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms

Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms (MUSA 3)

Source: ClinicalTrials.gov · Last updated 16 Oct 2026

Brief summary (registry, in English)

The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis assessing disease severity. Consecutive pre- and perimenopausal symptomatic and asymptomicasymptomatic women with an uterus presenting for gynaecological ultrasound exams will be asked to participate in the study. Routine gynecologicalgynaecological ultrasound exams will be performed and study participants will fill out a questionnaire on their symptoms (if any) and bleeding pattern. There will be one visit and no interventions.

Status (registry): Recruiting
Study type: Observational
Enrollment: 1000 (estimated)
First submitted: 13 May 2025
Start date: 15 Mar 2024
Primary completion date: 1 Feb 2028
Lead sponsor: Swiss GO Trial Group
Diseases: Endometriosis
NCT number: NCT07397715

What you commit to

Study type: Observational
Planned participants: 1000
From 15 Mar 2024 to the primary completion date, 1 Feb 2028
5 sites in 4 countries
Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

Prior myomectomy for FIGO 3-6 fibroids
Prior history of diagnosed intraabdominal adhesions (surgery)
Prior diagnosis of pelvic congestion syndrome
Prior surgery or treatment for deep infiltrating endometriosis

Other illness

Any serious underlying medical, psychiatric or psychological condition, which may interfere with the patient's capacity of discernment.
History of pelvic urogynaecologic surgery (TVT, mesh surgery, etc.)
Malignancy or premalignancy of uterus/cervix
Patients with coagulation disorders under current anticoagulation medication
Psychiatric disease precluding a reliable estimation of pain
Acute of chronic pelvic infection (cervicitis, endometritis, salpingitis, frozen pelvis)

Other

Missing written consent (study consent)
Postmenopausal women
Pregnancy
Acute other symptoms:
Urinary symptoms (dysuria, urgency, grade III stress incontinence)
Ovarian lesions
Sonographic signs of deep infiltrating endometriosis (DIE)
Intracavitary pathology (Fibroid 0-2, polyp, adhesions)
Retained products of conception
\>3 small fibroids below 2 cm in largest diameter FIGO 3-8 (i.e. the presence of three fibroids below 2cm is NOT considered an exclusion criterion)
Presence of any fibroid \>2cm.

Who the study is looking for

Women of pre- and perimenopausal age presenting for gynaecologic ultrasound exam giving voluntary informed written consent.
Symptomatic and asymptomatic women
Patients with hormonal contraceptives and Hormone Replacement Therapy (HRT) can be included, but information will be noted.

Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (5)

Sites in registry order. Pick your city on the disease page to sort them by distance.

Site	City	Country	Site status
UZ Leuven Coordinator of this site? Confirm its status	Leuven	Belgium	Recruiting
University Hospital Basel Coordinator of this site? Confirm its status	Basel	Switzerland	Recruiting
Kantonsspital Winterthur Coordinator of this site? Confirm its status	Winterthur	Switzerland	Recruiting
Hospital Universitari Dexeus Coordinator of this site? Confirm its status	Barcelona	Spain	Recruiting
Medical University of Silesia Coordinator of this site? Confirm its status	Sosnowiec	Poland	Recruiting

This page is information, not medical advice. Discuss any trial with your doctor.