NCT07397728Recruiting
" TREX1 Gene Mutations and Their Role in Systemic Lupus Erythematosus
TREX1 Gene Mutations and Their Role in Systemic Lupus Erythematosus: A Genotype-Phenotype Correlation Study
Source: ClinicalTrials.gov · Last updated 9 Feb 2026
Brief summary (registry, in English)
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by diverse clinical manifestations, prominently involving the skin.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 90 (estimated)
- First submitted
- 23 Jan 2026
- Start date
- 10 Jun 2025
- Primary completion date
- 1 Jun 2026
- Lead sponsor
- South Valley University
- Diseases
- Lupus (SLE)
- NCT number
- NCT07397728
What you commit to
- Study type: Observational
- Planned participants: 90
- From 10 Jun 2025 to the primary completion date, 1 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of biologic therapy or immunosuppressive pulses within one month.
Other illness
- Overlap autoimmune syndromes (e.g., dermatomyositis, systemic sclerosis).
- Systemic infection, malignancy, or pregnancy.
Who the study is looking for
- Adult aged 18-60 years
- Diagnosed as SLE per 2019 EULAR/ACR classification criteria.
- Presence of at least one cutaneous manifestation (acute, subacute, or chronic).
- Willing to provide written informed consent for participation and genetic testing
Age in the registry: 18 years to 60 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Qina University hospital, South Valley University Hospital Coordinator of this site? Confirm its status | Qina | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.