NCT07397754Recruiting
Sodium-rich COndiments Unifying Health and Taste
Source: ClinicalTrials.gov · Last updated 9 Feb 2026
Brief summary (registry, in English)
This research aims to develop an evidence-based classification for sodium-rich condiments (natremic index) based on their CVD-related risks. It is hypothesised that the acute cardiovascular and physiological response (effectively extrapolated to long-term CVD risks) to meals prepared with various sodium-rich condiments can be leveraged upon for the development of such an index that will systematically classify sodium-rich condiments based on the risk they present to cardiovascular health.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 32 (estimated)
- First submitted
- 18 Nov 2025
- Start date
- 22 Sept 2025
- Primary completion date
- 22 Sept 2026
- Lead sponsor
- Singapore Institute of Food and Biotechnology Innovation
- Diseases
- High blood pressure
- NCT number
- NCT07397754
What you commit to
- Study type: Interventional
- Planned participants: 32
- From 22 Sept 2025 to the primary completion date, 22 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prescribed and taking medication which may affect study outcomes (i.e. for blood pressure management, blood thinning etc.) in consultation with study physician (Prof Melvin Leow) and PI(Dr Darel Toh)
- Taking dietary supplements which may affect study outcomes one month prior to their first visit in consultation with study physician, PI and study team
- Drug abuse within last 5 years
Other illness
- History or known present diagnosis of hematological (G6PD and coagulation disorders), hepatic (hepatitis B and C), renal, gastrointestional or other relevant disease / disorders which may affect the outcomes of interest in consultation with study physician, PI and study team
- History of arteriovenous shunt or mastectomy
- History or present diagnosis of HIV and/or tuberculosis
- History of severe vasovagal syncope (blackouts or near faints) following blood draw
- Allergic or intolerance to intervention foods.
Lab values
- Type 1 or type 2 diabetes mellitus (i.e. fasting blood glucose ≥ 7.0 mmol/L or HbA1c ≥ 6.5 %)
Other
- Obesity (BMI ≥ 27.5 kg/m2)
- Women who are pregnant, lactating or planning pregnancy
- Excessive alcoholic beverage consumption \> 2 servings per day (1 serving defined as 360 mL beer, 150 mL wine or 45 mL distilled spirits)
- Smoking (cigarette, e-cigarette, cigar, pipe, vape)
- Engaging in habitual vigorous physical activity (as defined by physical activity questionnaire-PAR)
- Dislike or unwilling to consume intervention foods
- Photophobic (sensitivity to intense lights and colours), particularly to intense red lights
- Has sinus problems problems that affect taste and smell
- Involvement in other clinical studies that may influence the outcome of the study
- An ASTAR Staff.
- A study team member or their immediate family member
Who the study is looking for
- ≥ 50, \< 75 years old
- Male or postmenopausal female (self-reported)
- ≥ 50 kg body weight
- Systolic blood pressure (≥ 130, \< 160 mmHg) or diastolic blood pressure (≥ 85, \< 100 mmHg)
- Willing and able to follow intervention protocol
- Ability to identify basic tastes (determined by taste discrimination test)
- English speaking
Age in the registry: 50 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinical Nutrition Research Centre Coordinator of this site? Confirm its status | Singapore | Singapore | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.