NCT07398391Recruiting
Blood Pressure Care for Advancing Real-World Evidence (BPCARE)
Blood Pressure Care for Advancing Real-World Evidence (BPCARE): an RCT of Adherence
Source: ClinicalTrials.gov · Last updated 9 Feb 2026
Brief summary (registry, in English)
The goal of this randomized clinical trial is to determine whether a community health worker-delivered, multi-component behavioral intervention can improve antihypertensive medication adherence and blood pressure control among adult refugees with hypertension who are prescribed antihypertensive medications. The main questions it aims to answer are: 1. Does participation in the BPCARE intervention improve antihypertensive medication adherence compared to enhanced usual care? 2. Does participation in the BPCARE intervention improve blood pressure control and persistence over time compared to enhanced usual care? Researchers will compare participants randomized to the BPCARE intervention to those receiving enhanced usual care (hypertension information and a home blood pressure monitor) to determine the effects on medication adherence, blood pressure control, and persistence. Participants will: * Be randomly assigned to either the BPCARE intervention or enhanced usual care * Receive hypertension education and a home blood pressure monitor * Participate in community health worker-delivered sessions that include hypertension and medication education, motivational interviewing, problem-solving, and action planning (intervention arm only) * Complete questionnaires assessing medication adherence and related psychosocial factors * Have blood pressure monitored using connected home blood pressure devices * Complete pill counts to assess medication adherence over a nine-month follow-up period
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 250 (estimated)
- First submitted
- 27 Jan 2026
- Start date
- 9 Jan 2026
- Primary completion date
- 31 Aug 2029
- Lead sponsor
- University of California, San Diego
- Diseases
- High blood pressure
- NCT number
- NCT07398391
What you commit to
- Study type: Interventional
- Planned participants: 250
- From 9 Jan 2026 to the primary completion date, 31 Aug 2029
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current participation in another clinical trial that includes taking medications that may change blood pressure, or
Other illness
- A cardiovascular event or hospitalization for unstable angina within last 3 months,
Lab values
- Symptomatic heart failure within the past 6 months or left ventricular ejection fraction \< 35%,
- Major factors judged to be likely to significantly limit comprehension of or adherence to interventions including dementia, psychotic disorders, or affect ability to conduct pill counts
Other
- Individuals who are pregnant, planning on becoming pregnant within the next 7 months
- Any immediate family members participating in the trial.
Who the study is looking for
- Have a clinical diagnosis of hypertension determined at screening,
- Be at least 21 years of age,
- English as a second language,
- Be able to provide written informed consent and participate in study procedures,
- Have a last least one recorded automated clinic systolic BP reading of at least 130 mmHg within the past year OR at least one home SBP reading of ≥140 mmHg in the last year. AND/OR answer is in range of less than two months to "when was the last time you missed a dose of your hypertension medication?"
- Will not move out of San Diego in the next 6 months, and
- Have access to a mobile phone or computer with video telecommunication capacity (e.g. Zoom)
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California San Diego Coordinator of this site? Confirm its status | San Diego | United States | Active, not recruiting |
| Family Health Centers of San Diego Coordinator of this site? Confirm its status | San Diego | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.