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NCT07398586CompletedPhase 4

The Association Between Interleukin-7 Receptor Gene Polymorphism and the Risk of Ulcerative Colitis

The Association Between Interleukin-7 Receptor Gene Polymorphism and the Risk of Ulcerative Colitis as Well as the Response to Vedolizumab

Source: ClinicalTrials.gov · Last updated 10 Feb 2026

Brief summary (registry, in English)

From January 2020 to December 2024, diagnosed ulcerative colitis(UC) patients and gender- and age-matched normal controls were enrolled from the Department of Gastroenterology, the Second Affiliated Hospital of Wenzhou Medical University. Investigators' aim is to investigate the associations of IL-7R gene polymorphisms with the risk and clinicopathological characteristics of UC, and to analyze the effects of IL-7R gene variations on the clinical response of vedolizumab(VDZ) treatment in UC patients.

Status (registry)
Completed
Phase (registry)
Phase 4
Study type
Interventional
Enrollment
898 (actual)
First submitted
5 Jan 2026
Start date
1 Jan 2020
Primary completion date
31 Dec 2024
Lead sponsor
Second Affiliated Hospital of Wenzhou Medical University
NCT number
NCT07398586

What you commit to

  • Study type: Interventional · Phase 4
  • Participants enrolled: 898
  • From 1 Jan 2020 to the primary completion date, 31 Dec 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • -rheumatoid arthritis, systemic lupus erythematosus, intestinal tuberculosis, ischemic enteritis, radiation enteritis, tumors, etc.

Who the study is looking for

  • -diagnosed UC based on comprehensive clinical, colonoscopy, histopathological, laboratory, and radiographic examination results

Age in the registry: 18 years to 70 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
The Second Affiliated Hospital of Wenzhou Medical University
Coordinator of this site? Confirm its status
WenzhouChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.