NCT07398820Completed
IMPACT OF SEDENTARY BEHAVIOR IN THE HOMEOSTASIS OF THE DIGESTIVE ECOSYSTEM
Association of Sedentary Behavior and Physical Activity With Gut Transit Time and Its Effect on Gut Microbiota Inflammatory and Carcinogenic Potential
Source: ClinicalTrials.gov · Last updated 10 Feb 2026
Brief summary (registry, in English)
This study seeks to determine the relationship between sedentary behavior, gut transit, gut microbiota and polyps development. Will be conducted an evaluation which includes assessments of physical activity behaviors (through accelerometry), gut transit time (ingestion of two blue colored muffins), food ingestion (online nutritional survey), body composition (through bioimpedance), heart rate variability (with a heart rate monitor) and gut microbiota composition (from a fecal sample). The main goal of this study is to see if there is a relationship between high sedentary time and a slower gut transit time, altering gut microbiota favoring dysbiosis and promoting polyps development. For this objective, it will be described gut microbiota composition (identifying which bacteria are present in the gut and in what quantities are they found), physical activity and sedentary behaviors time, gut transit time (how long does it take to defecate after eating a meal) in order to relate these factors with the presence of polyps.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 80 (actual)
- First submitted
- 7 Nov 2024
- Start date
- 1 May 2023
- Primary completion date
- 30 Jun 2025
- Lead sponsor
- Clínica Universidad de los Andes
- Diseases
- Colorectal cancer
- NCT number
- NCT07398820
What you commit to
- Study type: Observational
- Participants enrolled: 80
- From 1 May 2023 to the primary completion date, 30 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Antibiotic treatment during the previous month.
- Previous digestive surgery except appendicitis.
Other illness
- Chronic inflammatory bowel disease (Crohn's disease, ulcerative colitis).
- Chronic constipation or diarrheic syndrome.
- Autoimmune disease (such as celiac disease, type 1 diabetes, etc.).
- HIV.
- Food allergies.
- Familial adenomatous polyposis or Lynch disease.
- Obesity (BMI\>30) and/or type 2 diabetes mellitus.
Other
- Daily use of aspirin.
- Chronic use of laxatives.
Who the study is looking for
- Both sexes.
- 40-60 years of age.
- Omnivorous diet.
- Negative or positive colonoscopy result with adenomatous polyp during the last 12 months.
Age in the registry: 40 years to 60 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clínica Universidad de los Andes Coordinator of this site? Confirm its status | Las Condes | Chile | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.