NCT07399535CompletedPhase 1
Clinical Investigation of Herbal Formulation and Its Efficacy in Polycystic Ovarian Syndrome
Source: ClinicalTrials.gov · Last updated 23 Jun 2026
Brief summary (registry, in English)
Polycystic Ovarian Syndrome (PCO) is a metabolic disorder that afflicts the women of childbearing age. An approximate of 5-10% women are the victim of this disorder. PCOS is a leading cause of infertility in females these days and is characterized by Hyperandrogenism, Chronic Anovulation, Impaired fertility, obesity, Hirsutism, Acne, Obesity, Metabolic disturbances (dyslipidemias, Hyperinsulinemia, insulin resistance, and type- 2 diabetes), and Endometrial Hyperplasia. This study will test a combination of herbal medications (Melats P) in women with PCOS to determine which works best to overcome infertility.
- Status (registry)
- Completed
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 116 (actual)
- First submitted
- 4 Dec 2025
- Start date
- 22 Feb 2025
- Primary completion date
- 22 Feb 2026
- Lead sponsor
- Jinnah Postgraduate Medical Centre
- NCT number
- NCT07399535
What you commit to
- Study type: Interventional · Phase 1
- Participants enrolled: 116
- From 22 Feb 2025 to the primary completion date, 22 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Subjects with known Cushing's syndrome.
- Subjects with uncontrolled thyroid disease.
- Subjects with diabetes mellitus.
- Subjects with uncontrolled hypertension.
- Subjects with other cardiovascular diseases.
- Subjects with acute or chronic infections.
- Subjects with any known malignancy.
Lab values
- Subjects with impaired renal function (serum creatinine \> 1.5 × ULN).
- Subjects with impaired liver function (serum ALT ≥ 2.5 × ULN).
Other
- Pregnant or lactating women.
- Subjects with late-onset congenital adrenal hyperplasia.
- Subjects with androgen-secreting tumors.
- Subjects with hyperprolactinemia.
Who the study is looking for
- Female subjects of reproductive age (18-40 years).
- Subjects with a diagnosis of polycystic ovary syndrome (PCOS) confirmed by clinician diagnostic criteria.
- Subjects with insulin resistance defined as HOMA-IR \> 2.00.
Age in the registry: 18 years to 40 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jinnah Postgraduate Medical Centre Coordinator of this site? Confirm its status | Karachi | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.