NCT07400198Recruiting
Gait and Bone Health in SMA
Identification of Gait-related Digital Biomarkers of Bone Health in Spinal Muscular Atrophy
Source: ClinicalTrials.gov · Last updated 18 Mar 2026
Brief summary (registry, in English)
The objective of this study is to understand how spatiotemporal and kinetic gait parameters are associated with bone health in pwSMA who are receiving DMT. We hypothesize that gait parameters are associated with BMD and can determine fracture risk in pwSMA. This is an observational study that involves one in-clinic visit (approximately 3 hours) with remote follow-up visits (approximately 15 minutes) every 3 months for 1 year to collect fracture and medical history. Each of the assessments included in this study are non-interventional and are not intended as a treatment nor are they at the level of standard of care.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 22 (estimated)
- First submitted
- 3 Dec 2025
- Start date
- 5 Mar 2026
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Jacqueline Montes
- Diseases
- Spinal muscular atrophy
- NCT number
- NCT07400198
What you commit to
- Study type: Observational
- Planned participants: 22
- From 5 Mar 2026 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Injury or surgery within previous 3 months that would impact ability to perform in-clinic gait assessments
Age
- Age less than 8 or over 50 years
Other
- Unwilling or unable to comply with all study procedures
Who the study is looking for
- Confirmed diagnosis of 5qSMA
- Between 8 and 50 years of age
- Able to walk 10 meters without support or an assistive device
- All participants who meet the inclusion criteria regardless of treatment status will be included, including those on adjuvant therapies, whether investigational or approved
Age in the registry: 8 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Columbia University Irving Medical Center Coordinator of this site? Confirm its status | New York | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.