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NCT07402031Recruiting

Predicting Weight Loss After Pharmacological or Surgical Treatment in Patients With Obesity

Research of Predictive Factors of Weight Loss After Pharmacological or Surgical Treatment in Patients Suffering From Obesity

Source: ClinicalTrials.gov · Last updated 14 May 2026

Brief summary (registry, in English)

As with other nutritional strategies, the clinical response to bariatric surgery can be highly variable, with weight regain being a frequent occurrence. Recent evidence on anti-obesity medication indicate similar inter-individual variability in clinical response. Among multiples factors, co-occurrence of eating disorders such as binge eating disorder has been implicated in insufficient clinical response. Improving our ability to predict how patients will respond to obesity treatment is necessary in order to tailor the care pathways we offer. The mechanisms involved in disturbances of eating behaviour before and after surgery remain largely unknown. This study aims to identify the predictive factors of weight loss after pharmacological or surgical treatment, as well as the cognitive and biological mechanisms that mediate this effect.

Status (registry)
Recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
13 Jan 2026
Start date
5 May 2026
Primary completion date
Jun 2032
Lead sponsor
Université Catholique de Louvain
Diseases
Obesity
NCT number
NCT07402031

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From 5 May 2026 to the primary completion date, Jun 2032
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Recent change in antidiabetic medication within the past 3 months.

Other illness

  • History of bariatric surgery (except gastric banding, provided it was removed more than five years ago).
  • Acute or progressive chronic disease
  • Inflammatory bowel disease;

Other

  • Legal protection
  • Pregnancy or breastfeeding
  • Alcohol consumption of more than 20 g/day
  • Digestive autonomic diabetic neuropathy.
  • Consumption of dietary supplements (stanols, probiotics, prebiotics or omega-3).
  • Following a vegan or gluten-free diet or being lactose intolerant.
  • Fibre consumption \>30 g/day

Who the study is looking for

  • Age between 18 and 65 years
  • Obesity, with bariatric surgery indicated after a multidisciplinary evaluation in case of surgical treatment.
  • Good physical and mental health, enabling informed consent.
  • French speaker

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Cliniques universitaires Saint-Luc
Coordinator of this site? Confirm its status
BrusselsBelgiumRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.