NCT07409129Not yet recruiting
Tubeless Strategy for Enhanced Recovery After Sublobar Resection
Tubeless Strategy Within an Enhanced Recovery After Surgery (ERAS) Protocol for Thoracoscopic Sublobar Resection: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 13 Feb 2026
Brief summary (registry, in English)
This is a prospective, randomized controlled clinical trial conducted at a single center. The study aims to evaluate whether a "tubeless" strategy can enhance recovery for patients undergoing minimally invasive thoracoscopic sublobar resection (wedge or segment resection) for small lung nodules. Participants will be randomly assigned to one of two groups: * The experimental group will receive the "tubeless" strategy, which includes non-endotracheal intubation anesthesia (using a laryngeal mask) and no routine chest tube drainage after surgery. * The control group will receive the traditional strategy, which includes double-lumen endotracheal intubation anesthesia and routine chest tube drainage. The main goal is to compare the rate of achieving high-quality fast-track recovery at 24 hours after surgery between the two groups. This study will provide evidence on whether the tubeless approach can help patients recover faster and more comfortably without compromising safety.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 138 (estimated)
- First submitted
- 24 Jan 2026
- Start date
- 1 Feb 2026
- Primary completion date
- 1 Jun 2026
- Lead sponsor
- The First Affiliated Hospital of Guangzhou Medical University
- Diseases
- Lung cancer
- NCT number
- NCT07409129
What you commit to
- Study type: Interventional
- Planned participants: 138
- From 1 Feb 2026 to the primary completion date, 1 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe cardiopulmonary dysfunction: FEV1 \< 50% predicted, DLCO \< 60% predicted, heart failure (NYHA class III-IV), or unstable angina.
- History of ipsilateral thoracic surgery.
- Active pulmonary infection, uncontrolled diabetes, or other comorbidities that increase surgical risk.
Other
- Severe pleural adhesions or fibrosis that would preclude non-intubated anesthesia or tubeless approach.
- Pregnancy or lactation (confirmed by urine test if applicable).
- Inability to tolerate one-lung ventilation due to anatomical or physiological reasons.
- Participation in another interventional trial within 30 days.
Who the study is looking for
- Age between 18 and 75 years.
- Scheduled for uniportal or multiportal video-assisted thoracoscopic surgery (VATS) for sublobar resection (wedge or segmentectomy).
- Presence of peripheral lung nodules ≤ 2 cm in diameter and ≤ 2 cm from the pleura, confirmed by CT scan.
- Ability to understand and provide written informed consent.
- American Society of Anesthesiologists (ASA) physical status I-III.
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of GZMU Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.