NCT07409350Not yet recruiting
A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs
Source: ClinicalTrials.gov · Last updated 13 Feb 2026
Brief summary (registry, in English)
This study includes finalization of the LINKED social network intervention to improve PrEP and MOUD uptake among people who inject drugs (PWID) in collaboration with an Expert Advisory Board and staff (N=16) at The Sidewalk Project (TSP), followed by a Hybrid Type II cluster randomized trial of the LINKED intervention (versus an equal-attention control) among N=372 people who inject drugs, with 6- and 12-month follow-up assessment of PrEP and MOUD uptake. The investigators will also evaluate implementation outcomes to inform future sustainable implementation of LINKED in harm reduction organizations.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 398 (estimated)
- First submitted
- 9 Feb 2026
- Start date
- Jan 2027
- Primary completion date
- Dec 2028
- Lead sponsor
- NYU Langone Health
- Diseases
- HIV
- NCT number
- NCT07409350
What you commit to
- Study type: Interventional
- Planned participants: 398
- From Jan 2027 to the primary completion date, Dec 2028
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Does not self-report injecting drugs in past 3 months;
- Currently on PrEP or MOUD
Other illness
- Self-reported HIV positive serostatus
Age
- Under age 18;
Other
- Aims 1 and 3:
- Individuals who are not current TSP staff members will be excluded from participation.
- Aim 2:
- Does not spend majority of time in the Los Angeles, CA area where recruited;
- Unable to complete surveys and groups sessions in English;
- Currently pregnant
- If a network recruit: does not present a valid recruitment coupon
Who the study is looking for
- Aim 1 - Virtual Focus Group
- Is 18 years or older
- Is a current TSP staff
- Is capable and willing to provide consent
- Aim 2 - Intervention
- 18 years or older
- Spend majority of their time in the Los Angeles, CA area where recruited
- Able to complete surveys and group sessions in English
- Self-report to have injected drugs in the past 3 months
- Self-reported HIV negative serostatus
- Not currently on PrEP or MOUD
- Not pregnant
- If a network recruit: presents a valid recruitment coupon
- Is capable and willing to provide consent
- Aim 3 - Virtual Focus Group/Surveys
- Is 18 years or older
- Is a current TSP staff
- Is capable and willing to provide consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The University Of Chicago Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| University of Southern California Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
| NYU Langone Health Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.