NCT07412275Not yet recruiting
Microwave Intervention Under Local Anesthesia
Prospective Study Evaluating the Feasibility of Focal Microwave Ablation Under Local Anesthesia in Patients With Localized Prostate Cancer
Source: ClinicalTrials.gov · Last updated 19 May 2026
Brief summary (registry, in English)
This study aims to evaluate the feasibility of performing a focal Targeted Microwave Ablation (TMA) procedure using Koelis TMA® under local anesthesia in patient with localized prostate cancer. Eligible patients will undergo the procedure under local anesthesia instead of general anesthesia or deep sedation as part of their routine clinical care. The primary objective is to assess the feasibility of completing the procedure under local anesthesia, defined by the proportion of patients in whom the procedure is successfully completed under local anesthesia. Secondary objectives include the assessment of safety, ease of performance, patient satisfaction, and the use of analgesic medication. This study is designed as a feasibility clinical investigation conducted in a routine clinical practice setting.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 9 Feb 2026
- Start date
- 15 Jun 2026
- Primary completion date
- 15 May 2027
- Lead sponsor
- Koelis
- Diseases
- Prostate cancer
- NCT number
- NCT07412275
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 15 Jun 2026 to the primary completion date, 15 May 2027
- 2 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Severe illness within the last 6 months before the screening visit, including any of the following: uncontrolled congestive heart failure, uncontrolled angina pectoris, myocardial infarction, stroke.
Other illness
- Uncontrolled coagulopathies or bleeding disorder
Other
- Ineligibility for a Koelis TMA® intervention
- Contraindication to general anesthesia and deep sedation.
- A person already participating in an interventional clinical study.
- A person placed under judicial protection, guardianship, or legal supervision and incapable of freely giving informed consent.
- Patient detained in an institution by medical or judicial decision.
Who the study is looking for
- Age\>18 years old
- Patient undergoing Koelis TMA® intervention
- Patient is suitable for general, local anesthesia as well as sedation
- No psychiatric illness that would prevent informed consent or optimal treatment and follow-up
- Free, informed and written consent, dated and signed by the patient and the investigator, no later than the day of inclusion and before any examination required by the study.
- Patient affiliated to a social security scheme or beneficiary of such a scheme in accordance with the regulations in force.
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institut Jules Bordet Coordinator of this site? Confirm its status | Brussels | Belgium | Unknown status |
| Hopital Cochin - Port Royal Coordinator of this site? Confirm its status | PARIS | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.