NCT07412795Completed
Non-Surgical Periodontal Therapy and Cardiac Biomarkers in Stable Angina
Effect of Non-Surgical Periodontal Therapy on Ischemia-Modified Albumin and Soluble ST2 in Patients With Stable Angina
Source: ClinicalTrials.gov · Last updated 27 Oct 2026
Brief summary (registry, in English)
The goal of this clinical study is to learn whether gum treatment can improve heart health. Researchers will compare blood markers related to heart disease before and after routine gum treatment. The main questions this study aims to answer are: Is gum disease a risk factor for heart disease? Can treating gum disease lower the risk of heart disease? Adults with stable angina (a type of heart disease) and adults without heart disease may take part in this study. All participants will receive routine, non-surgical gum treatment, which is a standard dental care procedure. This includes professional cleaning to remove plaque and tartar from the teeth and practical education on tooth brushing and cleaning between the teeth. The treatment will be performed by a single researcher and completed in one visit within about one hour. Participants will: Provide a blood sample before gum treatment Receive routine, non-surgical gum treatment Return after three months for a follow-up visit Provide a second blood sample This study does not involve experimental drugs or devices. Participation is voluntary, and there is no cost to participants. The results may help researchers better understand how gum health is related to heart health.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 27 Jan 2026
- Start date
- 20 Feb 2026
- Primary completion date
- 5 Jun 2026
- Lead sponsor
- Ondokuz Mayıs University
- Diseases
- Coronary artery disease
- NCT number
- NCT07412795
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 20 Feb 2026 to the primary completion date, 5 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Use of local or systemic antibiotics for the treatment of widespread infection
- History of acute myocardial infarction within the past 6 months
Age
- Age under 18 years
Other
- Unwillingness to participate in the study or to provide informed consent
- within the past 3 months
- Receipt of periodontal treatment within the past 6 months
- Pregnancy or lactation (for female participants)
Who the study is looking for
- Willingness to participate in the study and provide written informed consent
- Age 18 years or older
- No periodontal treatment within the past 6 months
- No use of local or systemic antibiotics within the past 3 months
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ondokuz Mayis University Coordinator of this site? Confirm its status | Samsun | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.