NCT07413640Recruiting
Variability of Microwave Ablation Volume Based on Clinical, Radiological, Biological, and Tissue Factors
Variability of Microwave Ablation Volume Based on Clinical, Radiological, Biological, and Tissue Factors : a Retrospective Study
Source: ClinicalTrials.gov · Last updated 21 Oct 2026
Brief summary (registry, in English)
Microwave ablation is a minimally invasive technique whose planning relies on manufacturer tables derived from ex vivo models that do not account for patient or tumor-specific factors. In clinical practice, the actual ablation volume often differs from the planned volume due to liver characteristics, vascular proximity, and tumor biology. This study aims to assess the variability between ablation small axis during percutaneous microwave ablation of liver lesions. The influence of patient-related (fibrosis, steatosis, portal flow) and tumor-related factors (location, histology, prior treatment) will be evaluated. Small axis and volume will be compared with volumes measured on immediate post-procedural CT and on CT/MRI at 6-12 weeks, accounting for expected tissue shrinkage.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 90 (estimated)
- First submitted
- 9 Feb 2026
- Start date
- 2 Feb 2026
- Primary completion date
- 31 Jul 2026
- Lead sponsor
- Central Hospital, Nancy, France
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT07413640
What you commit to
- Study type: Observational
- Planned participants: 90
- From 2 Feb 2026 to the primary completion date, 31 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Planned volume not available (no manufacturer data, not specified in the surgical report).
Other
- Two treatment cycles on the same lesion during the same session.
- Reoperation on the same lesion.
- No control imaging injected between 1 and 4 months post-procedure.
- Final ablation volume not measurable (e.g., artifacts, no injection on MRI).
- No definitive diagnosis of the nature of the tumor on imaging and no histology available.
Who the study is looking for
- Adult patients
- Treated with percutaneous hepatic microwave ablation under CT or ultrasound guidance
- Adult treated for one or more liver lesions
- Patients with available follow-up imaging
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHRU Nancy Coordinator of this site? Confirm its status | Vandœuvre-lès-Nancy | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.