NCT07413796Recruiting
Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures
Prospective Randomized Controlled Trial of Skin Closure Techniques in Oncological Cranial Neurosurgery: Interrupted Transdermal Sutures and Running Intradermal Suture.
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
The purpose of this study is to compare two commonly used methods of closing the skin after surgery for an intracranial tumor. Skin closure is one of the most important steps in neurosurgical procedures, as it has a major influence on how well the wound heals. In patients with brain tumors, proper wound healing is especially important because it may affect how soon additional treatments, such as radiotherapy or chemotherapy, can be started. There are different ways to close the skin after surgery, including running sutures and interrupted sutures. Both methods are widely used and considered safe. However, in oncological neurosurgery, there is limited scientific evidence comparing their effects, and the choice of technique is often based on the surgeon's personal experience. In this study, investigators will compare skin closure using running absorbable sutures with interrupted non-absorbable sutures. Investigators will evaluate how well, depending on used suturing methods, the wound heals and how often wound-related complications occur, such as infection, separation of the wound edges, or leakage of cerebrospinal fluid. Investigators believe that the results of this study will help improve wound care in patients undergoing neurosurgical treatment for brain tumors and, as a result, may contribute to better recovery and overall quality of life.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 382 (estimated)
- First submitted
- 4 Feb 2026
- Start date
- 1 Feb 2026
- Primary completion date
- 29 Feb 2028
- Lead sponsor
- Medical University of Warsaw
- Diseases
- Glioblastoma
- NCT number
- NCT07413796
What you commit to
- Study type: Interventional
- Planned participants: 382
- From 1 Feb 2026 to the primary completion date, 29 Feb 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Revision surgery due to recurrent brain tumor
Other
- Emergency neurosurgical procedure
- Scalp incision involving glabrous skin (e.g. forehead) or facial regions (e.g. eyebrow)
Who the study is looking for
- Male or female at least 18 years old
- Qualified for a craniotomy due to supratentorial intracranial tumor
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Neurosurgery of Medical University of Warsaw Coordinator of this site? Confirm its status | Warsaw | Poland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.