NCT07421661Not yet recruiting
Effect of Epilepsy and Antiepileptic Drug Therapy on Gastric Motility and Emptying With Point-Of-Care Gastric Ultrasound
Effect of Epilepsy and Antiepileptic Drug Therapy on Gastric Motility and Emptying by Comparing Gastric Volume With Point-Of-Care Gastric Ultrasound in Epileptic Patients After Standard CAS/ASA Fasting Guidelines
Source: ClinicalTrials.gov · Last updated 19 Feb 2026
Brief summary (registry, in English)
People with epilepsy often need surgery, but it is not fully known whether their stomachs empty food and liquids at the same rate as people without epilepsy. Some seizure medications, special diets, and nerve changes related to epilepsy may slow digestion, which could increase the risk of stomach contents entering the lungs during anesthesia. The purpose of this study is to find out whether people with epilepsy still have food or liquid in their stomachs before surgery, even after following standard fasting rules. To do this, researchers will use a simple bedside ultrasound scan of the stomach before surgery. The scan takes only a few minutes and does not involve needles, radiation, or pain and will determine what food and/or liquid may be present in the stomach before surgery. About 30 adults with epilepsy scheduled for surgery will take part in this study. The results of this study may help to inform whether or not the surgical fasting guidelines for epilepsy patients need to be modified. This is a prospective, observational study that will take place at University Hospital, London Health Sciences Centre.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 30 (estimated)
- First submitted
- 12 Feb 2026
- Start date
- 1 Apr 2026
- Primary completion date
- 1 Apr 2028
- Lead sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- Diseases
- Epilepsy
- NCT number
- NCT07421661
What you commit to
- Study type: Observational
- Planned participants: 30
- From 1 Apr 2026 to the primary completion date, 1 Apr 2028
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with continuous treatment on GLP/GIP 1 analogues without a washout period.
Other illness
- Neuro muscular/ neurodegenerative disorders with gastroparesis.
Other
- Refusal/withdrawal of consent.
- Noncompliance with fasting guidelines.
- Pregnancy.
- Parkinsons patients with proven gastroparesis.
- Diabetic neuropathy with gastroparesis
- Patients on Prokinetic agents (Metoclopramide/ Erythromycin)
- Uncontrolled hypothyroidism.
- Bowel obstruction
Who the study is looking for
- Diagnosis of epilepsy (confirmed by history or medical records and classified as per 2025 ILAE classification for seizures).
- Scheduled for elective neurologic (e.g., epilepsy surgery) or non-neurologic surgery under anesthesia.
- 18 years of age or older.
- Adherence to standard fasting guidelines (verified by patient report).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.