Optical Coherence Tomography in Acute Vessel Evaluation

Prior treatment

• Known or anticipated compliance problems with medical therapy
  • Angiographic exclusion criteria

Other illness

• Known severe heart failure with NYHA class equal or above III
• Active bleeding or coagulopathy
• Relevant allergies (contrast media, aspirin, clopidogrel, ticagrelor, everolimus)

Lab values

• Known ejection fraction \<30% before the admission
• Known renal failure with GFR \<30 ml/min/1.73 m2

Other

• Clinical exclusion criteria
• Intravascular imaging evaluation of any lesions at index procedure
• Cardiogenic shock
• Sustained ventricular tachycardia or ventricular fibrillation
• Planned CABG
• Life expectancy \<1 year
• Suspected inability to lie flat for the duration of the PCI procedure
• Inability to comply with the planned follow-up program
• Study lesion involving the Left main coronary artery
• Study lesion involving a true bifurcation lesion with a SB \>2.5mm
• Severe tortuosity
• Distal embolus
• Isolated coronary artery spasm
• Suspected spontaneous coronary artery dissection
• Chronic total occlusions with treatment indication and no antegrade intra plaque wire pass

• Clinical inclusion criteria:
• NSTEMI, STEMI
• Symptom duration \<12h for STEMI and \<48h for NSTEMI
• Age ≥ 18yrs
• Ability to provide written informed consent
  • Angiographic inclusion criteria:
• Angiographic signs of at least one possible culprit lesion. Signs including acute occlusion, partial occlusion, proximal embolus, haziness, high grade stenosis, stent thrombosis
• Wire in true distal lumen