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NCT07423130Completed

Indocyanine Green Fluorescence Angiography in Laparoscopic Sigmoid and Rectal Cancer Surgery

Indocyanine Green Fluorescence Angiography in Laparoscopic Sigmoid and Rectal Cancer Surgery: A Prospective Single-Center Observational Study With a Historical Control Group

Source: ClinicalTrials.gov · Last updated 20 Feb 2026

Brief summary (registry, in English)

Anastomotic leakage remains a major complication after colorectal cancer surgery. Indocyanine green fluorescence angiography (ICG-FA) allows real-time intraoperative assessment of bowel perfusion; however, its clinical impact remains controversial. This prospective single-center observational study evaluated the association between intraoperative use of ICG-FA and postoperative outcomes in patients undergoing laparoscopic sigmoid or rectal cancer surgery. Outcomes of patients assessed with ICG-FA were compared with those of a historical control cohort treated without fluorescence imaging.

Status (registry)
Completed
Study type
Observational
Enrollment
115 (actual)
First submitted
12 Feb 2026
Start date
Oct 2023
Primary completion date
Feb 2025
Lead sponsor
Jagiellonian University
NCT number
NCT07423130

What you commit to

  • Study type: Observational
  • Participants enrolled: 115
  • From Oct 2023 to the primary completion date, Feb 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Emergency surgery
  • Conversion to open surgery

Other illness

  • Known hypersensitivity to indocyanine green or iodine

Other

  • Pregnancy or breastfeeding
  • Planned end colostomy without anastomosis

Who the study is looking for

  • Age ≥ 18 years
  • Histologically confirmed or clinically suspected sigmoid or rectal adenocarcinoma
  • Elective laparoscopic resection with curative intent and planned colorectal/coloanal anastomosis
  • Ability to provide informed consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University Hospital in Krakow
Coordinator of this site? Confirm its status
KrakowPolandUnknown status

Related publications

This page is information, not medical advice. Discuss any trial with your doctor.