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NCT07423143Not yet recruiting

Menopausal Impact of Opportunistic Salpingectomy for Ovarian Cancer Prevention

Source: ClinicalTrials.gov · Last updated 20 Feb 2026

Brief summary (registry, in English)

The goal of this clinical trial is to find out whether removing the fallopian tubes at the time of hysterectomy leads to an earlier menopause. The study includes women under 55 years of age who previously underwent hysterectomy as participants in the HOPPSA trial, where they were randomly assigned to either removal of the fallopian tubes or no removal. The main question is: • Does removing the fallopian tubes at the time of hysterectomy lead to an earlier menopause? Researchers will compare women who had their fallopian tubes removed during hysterectomy with women who had hysterectomy alone to see whether menopause occurs earlier after tube removal. Age at menopause will be estimated by measuring follicle-stimulating hormone (FSH) in small blood samples collected on a paper card. Participants will: * Collect 4-5 drops of blood using a finger prick * Place the drops on a paper card and mail it to the researchers * Complete an online questionnaire These steps will be done twice, one year apart.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
2100 (estimated)
First submitted
12 Feb 2026
Start date
Mar 2026
Primary completion date
Feb 2029
Lead sponsor
Umeå University
NCT number
NCT07423143

What you commit to

  • Study type: Interventional
  • Planned participants: 2100
  • From Mar 2026 to the primary completion date, Feb 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Ongoing systemic hormonal treatment using sex steroids

Other illness

  • Cancer treatment affecting ovarian function

Other

  • Bilateral oophorectomy
  • Other treatments with major effects on ovarian function

Who the study is looking for

  • Having had hysterectomy for a benign indication
  • Less than 55 years at surgery
  • Was included in the ITT population of the HOPPSA register-based randomised controlled trial (R-RCT) of opportunistic salpingectomy
  • Informed consent

Age in the registry: 20 years to 65 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Umeå University
Coordinator of this site? Confirm its status
UmeåSwedenUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.