NCT07423884Not yet recruiting
Effect of a Low-Calorie MCT-Rich Traditional Minangkabau Diet on Obese Individuals
The Effect of a Low-Calorie Diet Rich in Medium-Chain Triglycerides Based on Traditional Minangkabau Foods on Lipid Profile, Leptin Levels, and DNA Methylation of the Leptin Gene Promoter in Individuals With Obesity
Source: ClinicalTrials.gov · Last updated 13 Apr 2026
Brief summary (registry, in English)
This study aims to investigate the effect of a low-calorie diet rich in medium-chain triglycerides (MCTs) based on traditional Minangkabau foods on metabolic biomarkers in individuals with obesity. The traditional Minangkabau foods used in this study consist primarily of coconut milk-based dishes, which contain coconut oil as a natural source of MCTs. The metabolic biomarkers assessed include body mass index (BMI), waist circumference, systolic and diastolic blood pressure, body fat percentage, fasting blood glucose levels, lipid profile, leptin concentrations, and DNA methylation of the leptin gene promoter. Based on these metabolic biomarker measurements, participants will be classified into metabolic obesity phenotypes, namely metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUHO). The researchers hypothesize that the provision of a low-calorie, MCT-rich diet based on traditional Minangkabau foods will have a significant effect on metabolic biomarkers and metabolic status in individuals with obesity.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 14 Feb 2026
- Start date
- Apr 2026
- Primary completion date
- May 2026
- Lead sponsor
- Andalas University
- Diseases
- Obesity
- NCT number
- NCT07423884
What you commit to
- Study type: Interventional
- Planned participants: 40
- From Apr 2026 to the primary completion date, May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking anti-diabetic or anti-lipid drugs
- Use of contraceptives or hormonal drugs
- In the treatment of radiotherapy or chemotherapyi
Other
- Did not come and could not be found at the time of research data collection
- Unable to follow the dietary arrangements as set
- Participants with obesity classified as Metabolically Healthy Obese (MHO)
Who the study is looking for
- Administrative staff of the Faculty of Medicine and the Faculty of Public Health, Andalas University, Padang, with obesity defined as a body mass index (BMI) ≥ 25 kg/m².
- Willing to participate in the study by providing written informed consent.
- Participants with obesity classified as Metabolically Unhealthy Obese (MUHO)
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Prof. Nur Indrawaty Lipoeto Coordinator of this site? Confirm its status | Padang | Indonesia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.