NCT07424365Recruiting
Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations
Investigation of Vagus Nerve Stimulation to Augment Executive Functioning
Source: ClinicalTrials.gov · Last updated 20 Feb 2026
Brief summary (registry, in English)
This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities. This process, called transcutaneous auricular vagus nerve stimulation (taVNS), could help improve brain function in both healthy individuals and people with Parkinson's disease (PD).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- First submitted
- 5 Feb 2026
- Start date
- May 2025
- Primary completion date
- May 2028
- Lead sponsor
- University of Colorado, Denver
- Diseases
- Parkinson disease
- NCT number
- NCT07424365
What you commit to
- Study type: Interventional
- Planned participants: 80
- From May 2025 to the primary completion date, May 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Electronic medical implants, such as pacemakers, cochlear prosthesis, neuro-stimulators.
Other illness
- Current uncontrolled and/or clinically significant medical condition.
- Abnormal ear anatomy or active ear infection.
- Uncorrected visual impairments that would interfere with task performance.
- (6) Other significant diseases or disorders that might impair study participation.
Who the study is looking for
- Individuals aged 18-65.
- Ability to sign informed consent.
- Ability to follow written and verbal instructions.
- For the PD group, a clinical diagnosis of Parkinson's disease without severe motor or cognitive impairments.
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinical Translational Research Center at CU Anschutz Coordinator of this site? Confirm its status | Aurora | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.