NCT07425106Enrolling by invitation
Comparative Study of High Performance Low-Cost Optical Coherence Tomography (Stage 1B, 2 and 3)
Comparative Study of High Performance Low-Cost Optical Coherence Tomography
Source: ClinicalTrials.gov · Last updated 25 Feb 2026
Brief summary (registry, in English)
The purpose of this study is to complete performance testing of our custom optical coherence tomography (OCT) device to verify it can deliver retinal images of similar quality to a commercial OCT device. We will then add an angle-resolved low coherence interferometry (a/LCI module) to the device to make measurements of retinal tissue structure.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 82 (estimated)
- First submitted
- 13 Feb 2026
- Start date
- 13 Feb 2026
- Primary completion date
- Feb 2027
- Lead sponsor
- Duke University
- Diseases
- Alzheimer disease
- NCT number
- NCT07425106
What you commit to
- Study type: Interventional
- Planned participants: 82
- From 13 Feb 2026 to the primary completion date, Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- potentially confounding ocular conditions, such as: glaucoma, current corneal injury, retinal damage, diabetes, corrected distance visual acuity worse than 20/40
- eyes that have had intraocular surgery or retinal surgery, other than cataract surgery
- Participants with Alzheimer's Disease:
- Inclusion:
- \- mild cognitive impairment (MCI) or dementia due to Alzheimer's disease, confirmed by A/T/N classification
- Healthy Controls:
- Exclusion:
- \- has a memory or other neurodegenerative diagnosis (including mild cognitive impairment, Parkinson's disease, Alzheimer's disease, traumatic brain injury, post-traumatic stress disorder)
- If two eyes satisfy the inclusion / exclusion criteria, both eyes will be included in the study. If only one eye satisfies the criteria, only the qualifying eye will be included in the study.
Who the study is looking for
- able to provide informed consent
Criteria the registry did not label
- All Participants:
Age in the registry: 18 years to 85 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Duke University Medical Center Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.