NCT07426302Enrolling by invitation
Virtual Reality-assisted Cognitive Rehabilitation in Autistic Youth With ADHD
A Randomized Controlled Trial on the Effectiveness of Virtual Reality-assisted Executive Function Training in Autistic and ADHD Youth
Source: ClinicalTrials.gov · Last updated 23 Feb 2026
Brief summary (registry, in English)
This study aims to evaluate the effectiveness of a virtual reality-based intervention using the Virtual Reality Rehabilitation System (VRRS) to improve executive functions in autistic and ADHD youth aged 8 to 18 years. Executive functions, such as working memory, cognitive flexibility, and inhibitory control, are frequently impaired in individuals with autism and/or ADHD and significantly affect daily functioning. Participants will be randomly assigned to either an experimental group that receives VRRS-assisted cognitive training or a control group that receives treatment as usual. The intervention includes gamified tasks within immersive virtual environments specifically designed to stimulate executive skills. The primary outcome is the change in executive function scores from baseline to post-intervention, assessed using validated neuropsychological instruments. The study adopts a randomized controlled design.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 16 Feb 2026
- Start date
- Jun 2023
- Primary completion date
- Jun 2026
- Lead sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
- Diseases
- Autism
- NCT number
- NCT07426302
What you commit to
- Study type: Interventional
- Planned participants: 50
- From Jun 2023 to the primary completion date, Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Lack of a clinical diagnosis of Autism Spectrum Disorder or Attention-Deficit/Hyperactivity Disorder
- Failure to sign informed consent from a parent or legal guardian;
- Presence of acute or chronic medical conditions
Age
- Age not between 8 and 18 years at enrollment
Other
- IQ \< 70
Who the study is looking for
- Age between 8 and 18 years at enrollment
- Clinical diagnosis of Autism Spectrum Disorder and Attention- Deficit/Hyperactivity Disorder, based on DSM-5 criteria
- IQ \> 70
- Signed Informed consent provided by a parent or legal guardian;
- No acute or chronic medical conditions
Age in the registry: 8 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Francesca Cucinotta Coordinator of this site? Confirm its status | Messina | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.